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Karger AG", "issue": "2", "license": [ { "start": { "date-parts": [ [ 2018, 1, 1 ] ], "date-time": "2018-01-01T00:00:00Z", "timestamp": 1514764800000 }, "content-version": "vor", "delay-in-days": 0, "URL": "https://www.karger.com/Services/SiteLicenses" }, { "start": { "date-parts": [ [ 2018, 1, 1 ] ], "date-time": "2018-01-01T00:00:00Z", "timestamp": 1514764800000 }, "content-version": "tdm", "delay-in-days": 0, "URL": "https://www.karger.com/Services/SiteLicenses" } ], "content-domain/domain": [], "content-domain/crossmark-restriction": false, "short-container-title": [ "Int Arch Allergy Immunol" ], "published-print/date-parts": [ [ 2018 ] ], "abstract": "<jats:p><b><i>Background:</i></b> English plantain (<i>Plantago lanceolata</i>) is an important weed pollen allergen source triggering allergic symptoms during summer. To elucidate genuine versus cross-reactive sensitization, we investigated IgE reactivity patterns and inhibition capacities of plantain-sensitized patients. <b><i>Methods:</i></b> Sera of 35 rhinoconjunctivitis patients from the north-east of France with positive skin prick tests (SPT) to <i>Plantago lanceolata</i> pollen were tested with clinically relevant allergen sources using ELISA, ImmunoCAP, and immunoblot inhibition. <b><i>Results:</i></b> The patients were multisensitized with additional reactivity to grass (94.3%), ash (74.3%), birch (71.4%), and mugwort (55.2%) pollen in SPT. Sensitization prevalence to allergen molecules was 34.3% (Pla l 1), 94.3% (Phl p 1/5), 60.0% (Ole e 1), 65.7% (Bet v 1), 37.1% (profilin), and 40.0% (CCD). In immunoblot, IgE reactivity to plantain pollen was inhibited with relevant pollen extracts and purified rPla l 1. Two sera did not reveal any IgE cross-reactivity, while reactivity to plantain was efficiently inhibited by grass pollen in the sera of 10 patients. The sera from 17 different patients could be inhibited by grass, birch, or ash pollen to varying degrees. Thus, only 37.1% of our patients demonstrated true plantain pollen sensitization, while 62.9% were solely positive due to IgE cross-reactive molecules from other clinically relevant pollen. <b><i>Conclusions:</i></b> Plantain pollen-sensitized patients are multi-reactors demonstrating varying and complex IgE-reactivity profiles. In vivo and in vitro tests using extracts are typically blurred due to the presence of homologous allergens or CCD in grass, birch, or ash pollen. So far, Pla l 1 represents the only indicative marker allergen for the diagnosis of genuine plantain pollen sensitization.</jats:p>", "DOI": "10.1159/000490004", "type": "journal-article", "created/date-parts": [ [ 2018, 6, 22 ] ], "created/date-time": "2018-06-22T21:01:19Z", "created/timestamp": 1529701279000, "page": "97-106", "source": "Crossref", "is-referenced-by-count": 4, "title": [ "Do <b><i>Plantago lanceolata</i></b> Skin Prick Test-Positive Patients Display IgE to Genuine Plantain Pollen Allergens? Investigation of Pollen Allergic Patients from the North-East of France" ], "prefix": "10.1159", "volume": "177", "author": [ { "given": "Teresa", "family": "Stemeseder", "sequence": "first", "affiliation": [] }, { "given": "Carine", "family": "Metz-Favre", "sequence": "additional", "affiliation": [] }, { "given": "Frederic", "family": "de Blay", "sequence": "additional", "affiliation": [] }, { "given": "Gabrielle", "family": "Pauli", "sequence": "additional", "affiliation": [] }, { "given": "Gabriele", "family": "Gadermaier", "sequence": "additional", "affiliation": [] } ], "member": "127", "published-online/date-parts": [ [ 2018, 6, 22 ] ], "container-title": [ "International Archives of Allergy and Immunology" ], "language": "en", "link": [ { "URL": "https://www.karger.com/Article/Pdf/490004", "content-type": "application/pdf", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://www.karger.com/Article/Pdf/490004", "content-type": "unspecified", "content-version": "vor", "intended-application": "similarity-checking" } ], "deposited/date-parts": [ [ 2022, 6, 21 ] ], "deposited/date-time": "2022-06-21T09:54:09Z", "deposited/timestamp": 1655805249000, "score": 0, "resource/primary/URL": "https://www.karger.com/Article/FullText/490004", "issued/date-parts": [ [ 2018 ] ], "references-count": 0, "journal-issue/issue": "2", "journal-issue/published-online/date-parts": [ [ 2018, 9, 19 ] ], "journal-issue/published-print/date-parts": [ [ 2018, 9, 27 ] ], "URL": "http://dx.doi.org/10.1159/000490004", "archive": [ "Portico" ], "relation/is-supplemented-by": [ { "id-type": "doi", "id": "10.6084/m9.figshare.6652790", "asserted-by": "subject" } ], "ISSN": [ "1018-2438", "1423-0097" ], "issn-type": [ { "value": "1018-2438", "type": "print" }, { "value": "1423-0097", "type": "electronic" } ], "subject": [ "Immunology", "General Medicine", "Immunology and Allergy" ], "published/date-parts": [ [ 2018 ] ] } }, { "id": 4, "value": { "indexed/date-parts": [ [ 2023, 9, 14 ] ], "indexed/date-time": "2023-09-14T19:43:30Z", "indexed/timestamp": 1694720610787, "reference-count": 35, "publisher": "Elsevier BV", "license": [ { "start": { "date-parts": [ [ 2018, 11, 1 ] ], "date-time": "2018-11-01T00:00:00Z", "timestamp": 1541030400000 }, "content-version": "tdm", "delay-in-days": 0, "URL": "https://www.elsevier.com/tdm/userlicense/1.0/" } ], "content-domain/domain": [ "elsevier.com", "sciencedirect.com" ], "content-domain/crossmark-restriction": true, "short-container-title": [ "Journal of Membrane Science" ], "published-print/date-parts": [ [ 2018, 11 ] ], "DOI": "10.1016/j.memsci.2018.08.024", "type": "journal-article", "created/date-parts": [ [ 2018, 8, 30 ] ], "created/date-time": "2018-08-30T18:57:31Z", "created/timestamp": 1535655451000, "page": "346-366", "update-policy": "http://dx.doi.org/10.1016/elsevier_cm_policy", "source": "Crossref", "is-referenced-by-count": 50, "title": [ "Optimization of multistage membrane gas separation processes. Example of application to CO2 capture from blast furnace gas" ], "prefix": "10.1016", "volume": "566", "author": [ { "given": "Álvaro A.", "family": "Ramírez-Santos", "sequence": "first", "affiliation": [] }, { "given": "M.", "family": "Bozorg", "sequence": "additional", "affiliation": [] }, { "ORCID": "http://orcid.org/0000-0003-4843-8709", "authenticated-orcid": false, "given": "B.", "family": "Addis", "sequence": "additional", "affiliation": [] }, { "ORCID": "http://orcid.org/0000-0002-3357-9608", "authenticated-orcid": false, "given": "V.", "family": "Piccialli", "sequence": "additional", "affiliation": [] }, { "given": "C.", "family": "Castel", "sequence": "additional", "affiliation": [] }, { "ORCID": "http://orcid.org/0000-0003-4400-1921", "authenticated-orcid": false, "given": "E.", "family": "Favre", "sequence": "additional", "affiliation": [] } ], "member": "78", "container-title": [ "Journal of Membrane Science" ], "language": "en", "link": [ { "URL": "https://api.elsevier.com/content/article/PII:S0376738818317824?httpAccept=text/xml", "content-type": "text/xml", "content-version": "vor", "intended-application": "text-mining" }, { "URL": "https://api.elsevier.com/content/article/PII:S0376738818317824?httpAccept=text/plain", "content-type": "text/plain", "content-version": "vor", "intended-application": "text-mining" } ], "deposited/date-parts": [ [ 2020, 4, 20 ] ], "deposited/date-time": "2020-04-20T21:56:32Z", "deposited/timestamp": 1587419792000, "score": 0, "resource/primary/URL": "https://linkinghub.elsevier.com/retrieve/pii/S0376738818317824", "issued/date-parts": [ [ 2018, 11 ] ], "references-count": 35, "alternative-id": [ "S0376738818317824" ], "URL": "http://dx.doi.org/10.1016/j.memsci.2018.08.024", "ISSN": [ "0376-7388" ], "issn-type": [ { "value": "0376-7388", "type": "print" } ], "subject": [ "Filtration and Separation", "Physical and Theoretical Chemistry", "General Materials Science", "Biochemistry" ], "published/date-parts": [ [ 2018, 11 ] ], "assertion": [ { "value": "Elsevier", "name": "publisher", "label": "This article is maintained by" }, { "value": "Optimization of multistage membrane gas separation processes. 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All rights reserved.", "name": "copyright", "label": "Copyright" } ] } }, { "id": 5, "value": { "indexed/date-parts": [ [ 2023, 9, 16 ] ], "indexed/date-time": "2023-09-16T07:07:13Z", "indexed/timestamp": 1694848033009, "reference-count": 43, "publisher": "American Geophysical Union (AGU)", "issue": "1", "license": [ { "start": { "date-parts": [ [ 2019, 1, 11 ] ], "date-time": "2019-01-11T00:00:00Z", "timestamp": 1547164800000 }, "content-version": "vor", "delay-in-days": 0, "URL": "http://creativecommons.org/licenses/by-nc-nd/4.0/" } ], "funder": [ { "DOI": "10.13039/100011102", "name": "Seventh Framework Programme", "doi-asserted-by": "publisher", "award": [ "320839" ] }, { "DOI": "10.13039/501100005416", "name": "Norges Forskningsråd", "doi-asserted-by": "publisher", "award": [ "208028/F50" ] } ], "content-domain/domain": [ "agupubs.onlinelibrary.wiley.com" ], "content-domain/crossmark-restriction": true, "short-container-title": [ "JGR Atmospheres" ], "published-print/date-parts": [ [ 2019, 1, 16 ] ], "abstract": "<jats:title>Abstract</jats:title><jats:p>Terrestrial gamma ray flashes (TGFs) are sub‐millisecond bursts of high energetic gamma radiation associated with intracloud flashes in thunderstorms. In this paper we use the simultaneity of lightning detections by World Wide Lightning Location Network to find TGFs in the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) data that are too faint to be identified by standard search algorithms. A similar approach has been used in an earlier paper, but here we expand the data set to include all years of RHESSI + World Wide Lightning Location Network data and show that there is a population of observationally weak TGFs all the way down to 0.22 of the RHESSI detection threshold (three counts in the detector). One should note that the majority of these are “normal” TGFs that are produced further away from the subsatellite point (and experience a 1/<jats:italic>r</jats:italic><jats:sup>2</jats:sup> effect) or produced at higher latitudes with a lower tropoause and thus experience increased atmospheric attenuation. This supports the idea that the TGF production rate is higher than currently reported. We also show that compared to lightning flashes, TGFs are more partial to ocean and coastal regions than over land.</jats:p>", "DOI": "10.1029/2018jd029272", "type": "journal-article", "created/date-parts": [ [ 2018, 11, 29 ] ], "created/date-time": "2018-11-29T21:55:12Z", "created/timestamp": 1543528512000, "page": "287-298", "update-policy": "http://dx.doi.org/10.1002/crossmark_policy", "source": "Crossref", "is-referenced-by-count": 10, "title": [ "Observationally Weak TGFs in the RHESSI Data" ], "prefix": "10.1029", "volume": "124", "author": [ { "ORCID": "http://orcid.org/0000-0002-9212-1904", "authenticated-orcid": false, "given": "K. 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Tel: (919)286-6933; Fax: (919)416-5832. Email: tracey.holsinger@med.va.gov" ] }, { "name": "Michael Helms", "affiliations": [ "Duke University Medical Center, Psychiatry, Durham, NC, USA" ] }, { "name": "Brenda Plassman", "affiliations": [ "Duke University Medical Center, Psychiatry, Durham, NC, USA" ] } ], "articleId": [ "afm016" ], "accessCondition/contentType": "isOpenAccess", "accessCondition/value": "bronzeOpenAccess", "arkIstex": "ark:/67375/HXZ-J1BLQKH4-3", "abstract": "Background: previous research has reported that greater intelligence in early life is associated with longer lifespan. Whether this relationship is mediated by genetic factors or environmental factors, some of which could be modified by an individual, is unclear. Objective: we examined the association between intelligence test scores, obtained during the 1940s, and age at death in a group of 492 male twin pairs, members of the National Academy of Sciences - National Research Council Twins Registry of WWII veterans. Design: using self-report information collected in th 1960s, we xamined whether modifiable risk factors for mortality, such as use of tobacco and alcohol, cardiovascular disease, and body mass index altered the association between intelligence and longevity. Results: when each member of a twin pair was treated as an independent observation, higher intelligence test scores were associated with longer life span (P = 0.0002). Modifiable risk factors were associated with life span as expected. However, in co-twin control analyses in which one twin served as the control for the other twin, neither intelligence nor any modifiable risk factors showed a significant association with life span. 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Storti Foundation" }, "biblScope": [ { "unit": "volume", "_t": "101" }, { "unit": "issue", "_t": "12" }, { "unit": "pp", "_t": "1603-1610" } ], "date": { "type": "datePub", "_t": "2016-12" } } }, "idno": [ { "type": "doi", "_t": "10.3324/haematol.2016.148908" }, { "type": "pubmed", "_t": "27515247" } ] } }, "profileDesc": { "langUsage": { "language": { "ident": "en", "_t": "English" } }, "textClass": { "keywords": { "scheme": "author", "term": { "xml_lang": "en", "_t": "quality" } }, "classCode": [ { "scheme": "halDomain", "n": "sdv.spee", "_t": "Life Sciences [q-bio]/Santé publique et épidémiologie" }, { "scheme": "halDomain", "n": "shs.eco", "_t": "Humanities and Social Sciences/Economics and Finance" }, { "scheme": "halDomain", "n": "shs.psy", "_t": "Humanities and Social Sciences/Psychology" }, { "scheme": "halDomain", "n": "sdv.mhep.psm", "_t": "Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health" }, { "scheme": "halTypology", "n": "ART", "_t": "Journal articles" }, { "scheme": "halOldTypology", "n": "ART", "_t": "Journal articles" }, { "scheme": "halTreeTypology", "n": "ART", "_t": "Journal articles" } ] }, "abstract": { "xml_lang": "en", "p": { "_t": "Cardiovascular conditions are serious long-term complications of childhood acute leukemia. However, few studies have investigated the risk of metabolic syndrome, a known predictor of cardiovascular disease, in patients treated without hematopoietic stem cell transplantation. We describe the overall and age-specific prevalence, and the risk factors for metabolic syndrome and its components in the L.E.A. (Leucémie de l'Enfant et de l'Adolescent) French cohort of childhood acute leukemia survivors treated without hematopoietic stem cell transplantation. The study included 650 adult patients (mean age at evaluation: 24.2 years; mean follow-up after leukemia diagnosis: 16.0 years). The prevalence of metabolic syndrome was 6.9% (95% CI 5.1-9.2). The age-specific cumulative prevalence at 20, 25, 30 and 35 years of age was 1.3%, 6.1%, 10.8% and 22.4%, respectively. The prevalence of decreased high-density lipoprotein cholesterol, increased triglycerides, increased fasting glucose, increased blood pressure and increased abdominal circumference was 26.8%, 11.7%, 5.8%, 36.7% and 16.7%, respectively. Risk factors significantly associated with metabolic syndrome in the multivariate analysis were male sex (OR 2.64; 95% CI 1.32-5.29), age at last evaluation (OR 1.10; 95% CI 1.04-1.17) and body mass index at diagnosis (OR 1.15; 95% CI 1.01-1.32). The cumulative steroid dose was not a significant risk factor. Irradiated and non-irradiated patients exhibited different patterns of metabolic abnormalities, with more frequent abdominal obesity in irradiated patients and more frequent hypertension in non-irradiated patients. Survivors of childhood acute leukemia are at risk of metabolic syndrome, even when treated without hematopoietic stem cell transplantation or central nervous system irradiation. 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However, few studies have investigated the risk of metabolic syndrome, a known predictor of cardiovascular disease, in patients treated without hematopoietic stem cell transplantation. We describe the overall and age-specific prevalence, and the risk factors for metabolic syndrome and its components in the L.E.A. (Leucémie de l'Enfant et de l'Adolescent) French cohort of childhood acute leukemia survivors treated without hematopoietic stem cell transplantation. The study included 650 adult patients (mean age at evaluation: 24.2 years; mean follow-up after leukemia diagnosis: 16.0 years). The prevalence of metabolic syndrome was 6.9% (95% CI 5.1-9.2). The age-specific cumulative prevalence at 20, 25, 30 and 35 years of age was 1.3%, 6.1%, 10.8% and 22.4%, respectively. The prevalence of decreased high-density lipoprotein cholesterol, increased triglycerides, increased fasting glucose, increased blood pressure and increased abdominal circumference was 26.8%, 11.7%, 5.8%, 36.7% and 16.7%, respectively. Risk factors significantly associated with metabolic syndrome in the multivariate analysis were male sex (OR 2.64; 95% CI 1.32-5.29), age at last evaluation (OR 1.10; 95% CI 1.04-1.17) and body mass index at diagnosis (OR 1.15; 95% CI 1.01-1.32). The cumulative steroid dose was not a significant risk factor. Irradiated and non-irradiated patients exhibited different patterns of metabolic abnormalities, with more frequent abdominal obesity in irradiated patients and more frequent hypertension in non-irradiated patients. Survivors of childhood acute leukemia are at risk of metabolic syndrome, even when treated without hematopoietic stem cell transplantation or central nervous system irradiation. A preventive approach with regular screening for cardiovascular risk factors is recommended. clinicaltrials.gov identifier:01756599. Copyright© Ferrata Storti Foundation.", "abstract/en": "Cardiovascular conditions are serious long-term complications of childhood acute leukemia. However, few studies have investigated the risk of metabolic syndrome, a known predictor of cardiovascular disease, in patients treated without hematopoietic stem cell transplantation. We describe the overall and age-specific prevalence, and the risk factors for metabolic syndrome and its components in the L.E.A. (Leucémie de l'Enfant et de l'Adolescent) French cohort of childhood acute leukemia survivors treated without hematopoietic stem cell transplantation. The study included 650 adult patients (mean age at evaluation: 24.2 years; mean follow-up after leukemia diagnosis: 16.0 years). The prevalence of metabolic syndrome was 6.9% (95% CI 5.1-9.2). The age-specific cumulative prevalence at 20, 25, 30 and 35 years of age was 1.3%, 6.1%, 10.8% and 22.4%, respectively. The prevalence of decreased high-density lipoprotein cholesterol, increased triglycerides, increased fasting glucose, increased blood pressure and increased abdominal circumference was 26.8%, 11.7%, 5.8%, 36.7% and 16.7%, respectively. Risk factors significantly associated with metabolic syndrome in the multivariate analysis were male sex (OR 2.64; 95% CI 1.32-5.29), age at last evaluation (OR 1.10; 95% CI 1.04-1.17) and body mass index at diagnosis (OR 1.15; 95% CI 1.01-1.32). The cumulative steroid dose was not a significant risk factor. Irradiated and non-irradiated patients exhibited different patterns of metabolic abnormalities, with more frequent abdominal obesity in irradiated patients and more frequent hypertension in non-irradiated patients. Survivors of childhood acute leukemia are at risk of metabolic syndrome, even when treated without hematopoietic stem cell transplantation or central nervous system irradiation. A preventive approach with regular screening for cardiovascular risk factors is recommended. clinicaltrials.gov identifier:01756599. 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