BioMed Central biomed B Bi Bio BioM BLOCKSTART PAGESTART NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 0 0 no 0 10 0 0 0 0 1
Page 1 page P Pa Pag Page BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 0 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 () 2 10 0 0 0 0 0
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 0 0 no 0 10 0 0 0 0 1
Open Access open O Op Ope Open BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 0 no 0 10 0 0 0 0 1
Research article research R Re Res Rese BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 0 0 no 0 10 0 0 0 0 1
High-resolution array high-resolution H Hi Hig High BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 0 - 1 10 0 0 0 0 1
carcinogenesis carcinogenesis carcinogenesis c ca car carc BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 no 0 2 0 0 0 0 1
Susanna L susanna S Su Sus Susa BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 0 0 ,,,-,, 6 10 0 0 0 0 1
Carlos Caldas carlos C Ca Car Carl BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 0 0 * 1 5 0 0 0 0 1
Address: 1 address: A Ad Add Addr BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 1 :/,,,, 6 9 0 0 0 0 1
Institute and institute I In Ins Inst BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 1 ,,,, 4 10 0 0 0 0 1
NHS Trust nhs N NH NHS NHS BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 0 1 ,, 2 3 0 0 0 0 1
Email: Susanna email: E Em Ema Emai BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 0 2 :-...;-....;--- 15 10 0 0 0 0 1
Feung.Chin@cancer.org.uk; Ian feung.chin@cancer.org.uk; F Fe Feu Feun BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 0 2 ...;-...;-...; 14 9 0 0 0 0 1
Paul AW paul P Pa Pau Paul BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 0 2 *-.. 4 2 0 0 0 0 1
* Corresponding * * * * * BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 0 2 * 1 1 0 0 0 0 1
Abstract Abstract abstract A Ab Abs Abst BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 3 no 0 10 0 0 0 0 1
Background: Rearrangement background: B Ba Bac Back BLOCKSTART PAGEIN SAMEFONT LOWERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 3 :() 3 9 0 0 0 0 1
cancers such cancers c ca can canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 3 .(. 3 10 0 0 0 0 1
Mb – mb M Mb Mb Mb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 0 3 –.),-. 6 8 0 0 0 0 1
Rearrangements in rearrangements R Re Rea Rear BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 3 --, 3 9 0 0 0 0 1
30 Mb 30 3 30 30 30 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 0 3 , 1 9 0 0 0 0 1
suppressor genes. suppressor s su sup supp BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 3 . 1 1 0 0 0 0 1
Methods: We methods: M Me Met Meth BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 4 :- 2 9 0 0 0 0 1
and six and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 4 . 1 10 0 0 0 0 1
characterised, using characterised, c ch cha char BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 4 ,.,- 4 9 0 0 0 0 1
tumours validated tumours t tu tum tumo BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 4 . 1 7 0 0 0 0 1
Results: We results: R Re Res Resu BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 6 :, 2 9 0 0 0 0 1
loss or loss l lo los loss BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 6 . 1 9 0 0 0 0 1
at least at a at at at BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 6 :.. 3 10 0 0 0 0 1
(0 Mb (0 ( (0 (0 (0 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 6 (–.)., 6 9 0 0 0 0 1
mutation of mutation m mu mut muta BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 6 ..–. 4 9 0 0 0 0 1
Mb in mb M Mb Mb Mb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 0 6 ,,..(.– 7 9 0 0 0 0 1
23.4 Mb) 23.4 2 23 23. 23.4 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 6 .). 3 4 0 0 0 0 1
Conclusion: The conclusion: C Co Con Conc BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 8 : 1 10 0 0 0 0 1
of potential of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 8 , 1 9 0 0 0 0 1
suppressor gene. suppressor s su sup supp BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 8 . 1 1 0 0 0 0 1
Background Background background B Ba Bac Back BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 9 no 0 10 0 0 0 0 1
Rearrangements of rearrangements R Re Rea Rear BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 9 () 2 9 0 0 0 0 1
are one are a ar are are BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 9 [- 2 10 0 0 0 0 1
3], pancreatic 3], 3 3] 3], 3], BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 9 ],[] 4 9 0 0 0 0 1
[5]. Although [5]. [ [5 [5] [5]. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 9 []. 3 8 0 0 0 0 1
using a using u us usi usin BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 9 ,, 2 10 0 0 0 0 1
Published: 7 published: P Pu Pub Publ BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 10 : 1 10 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 0 10 ,::./--- 8 10 0 0 0 0 1
Received: 4 received: R Re Rec Rece BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 10 : 1 8 0 0 0 0 1
Accepted: 7 accepted: A Ac Acc Acce BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 10 : 1 10 0 0 0 0 1
This article this T Th Thi This BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 10 :://../-// 10 10 0 0 0 0 1
© 2008 © © © © © BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 0 10 ;. 2 3 0 0 0 0 1
This is this T Th Thi This BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 10 (://.///.), 11 10 0 0 0 0 1
which permits which w wh whi whic BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 10 ,,,. 4 8 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT HIGHERFONT 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 0 0 ,: 2 10 0 0 1 1 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 0 0 ://../-// 9 10 0 0 1 1 1
Page 2 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 0 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 () 2 10 0 0 0 0 0
(comparative genomic (comparative ( (c (co (com BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 (), 3 8 0 0 0 0 1
LOH (loss loh L LO LOH LOH BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 1 0 0 0 0 0 0 0 0 ()[-],- 7 10 0 0 0 0 1
tion, with tion, t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 ,- 2 10 0 0 0 0 1
cussed below, cussed c cu cus cuss BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 , 1 10 0 0 0 0 1
small number small s sm sma smal BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 0 0 . 1 9 0 0 0 0 1
Loss of loss L Lo Los Loss BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 0 () 2 9 0 0 0 0 1
are at are a ar are are BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 0 , 1 9 0 0 0 0 1
8p23, 8p22, 8p23, 8 8p 8p2 8p23 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 0 ,,, 3 9 0 0 0 0 1
types [6-8]. types t ty typ type BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 0 [-]. 4 10 0 0 0 0 1
over 1 over o ov ove over BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 0 , 1 8 0 0 0 0 1
region of region r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 0 no 0 8 0 0 0 0 1
(1.0 Mb) (1.0 ( (1 (1. (1.0 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 0 (.)(.).[]. 10 9 0 0 0 0 1
of this of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 0 - 1 9 0 0 0 0 1
cinomas identifies cinomas c ci cin cino BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 (.)- 4 8 0 0 0 0 1
ond highest ond o on ond ond BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 0 , 1 9 0 0 0 0 1
D8S1827 (14.9 d8s1827 D D8 D8S D8S1 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 0 0 (.)[]. 6 5 0 0 0 0 1
Cytogenetic and cytogenetic C Cy Cyt Cyto BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 0 2 no 0 9 0 0 0 0 1
is frequently is i is is is BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 2 no 0 9 0 0 0 0 1
that breaks that t th tha that BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 2 -[,]... 7 9 0 0 0 0 1
and 38.5 and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 2 .,, 3 9 0 0 0 0 1
that has that t th tha that BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 2 , 1 10 0 0 0 0 1
tiling-path BAC tiling-path t ti til tili BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 2 -[,]. 5 8 0 0 0 0 1
breakpoints are breakpoints b br bre brea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 2 ,,- 3 9 0 0 0 0 1
mosome band mosome m mo mos moso BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 2 no 0 8 0 0 0 0 1
NRG1 (neuregulin nrg1 N NR NRG NRG1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 2 ()(.; 5 8 0 0 0 0 1
Build 36) build B Bu Bui Buil BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 2 )[,]. 5 9 0 0 0 0 1
this breakpoint this t th thi this BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 2 no 0 8 0 0 0 0 1
array CGH array a ar arr arra BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 2 no 0 9 0 0 0 0 1
regions identified regions r re reg regi BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 2 . 1 7 0 0 0 0 1
The other the T Th The The BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 3 , 1 9 0 0 0 0 1
at least at a at at at BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 3 ,- 2 9 0 0 0 0 1
10–25% of 10–25% 1 10 10– 10–2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 3 –,[,- 5 9 0 0 0 0 1
15]. This 15]. 1 15 15] 15]. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 3 ]. 2 9 0 0 0 0 1
FGFR1 (Fibroblast fgfr1 F FG FGF FGFR BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 3 ()[], 5 9 0 0 0 0 1
member of member m me mem memb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 3 ( 1 9 0 0 0 0 1
Factor Receptor factor F Fa Fac Fact BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 0 3 ),- 3 9 0 0 0 0 1
fication. However, fication. f fi fic fica BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 3 ., 2 9 0 0 0 0 1
FGFR1 is fgfr1 F FG FGF FGFR BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 3 no 0 9 0 0 0 0 1
amplification and amplification a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 3 no 0 9 0 0 0 0 1
suggested [11,13-15,17,18]. suggested s su sug sugg BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 3 [,-,,].- 8 9 0 0 0 0 1
amplification shows amplification a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 0 3 no 0 9 0 0 0 0 1
sub-regions of sub-regions s su sub sub- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 3 -[,],- 6 10 0 0 0 0 1
ity that ity i it ity ity BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 0 3 -- 2 9 0 0 0 0 1
12. 12. 12. 1 12 12. 12. BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 0 3 . 1 0 0 0 0 0 1
Array CGH array A Ar Arr Arra BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 5 no 0 8 0 0 0 0 1
[19] and [19] [ [1 [19 [19] BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 5 [][]- 5 8 0 0 0 0 1
tern of tern t te ter tern BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 5 no 0 10 0 0 0 0 1
individual changes individual i in ind indi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 5 . 1 8 0 0 0 0 1
Two tiling-path two T Tw Two Two BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 5 - 1 8 0 0 0 0 1
on seven on o on on on BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 5 [][]. 5 10 0 0 0 0 1
mentions two mentions m me men ment BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 5 [].- 4 8 0 0 0 0 1
whole of whole w wh who whol BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 6 ., 2 9 0 0 0 0 1
although we although a al alt alth BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 6 no 0 9 0 0 0 0 1
number variation number n nu num numb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 6 (). 3 8 0 0 0 0 1
changes – changes c ch cha chan BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 1 6 –– 2 9 0 0 0 0 1
the ZR-75-30 the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 6 --- 3 8 0 0 0 0 1
plementary data, plementary p pl ple plem BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 6 ,- 2 9 0 0 0 0 1
ther analysis. ther t th the ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 6 . 1 10 0 0 0 0 1
8p11-12 in 8p11-12 8 8p 8p1 8p11 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 6 --[]. 5 4 0 0 0 0 1
Overall the overall O Ov Ove Over BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 7 ,- 2 9 0 0 0 0 1
cially distal cially c ci cia cial BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 7 ,, 2 10 0 0 0 0 1
the lack the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 7 - 1 9 0 0 0 0 1
the lack the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 7 no 0 9 0 0 0 0 1
LOH as loh L LO LOH LOH BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 1 0 0 0 0 0 0 1 7 . 1 9 0 0 0 0 1
CGH suggests cgh C CG CGH CGH BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 1 7 , 1 9 0 0 0 0 1
or just or o or or or BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 7 ,[], 4 9 0 0 0 0 1
LOH analysis loh L LO LOH LOH BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 1 0 0 0 0 0 0 1 7 no 0 9 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 7 [-]. 4 9 0 0 0 0 1
that might that t th tha that BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 7 no 0 9 0 0 0 0 1
across different across a ac acr acro BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 7 [], 3 9 0 0 0 0 1
changes on changes c ch cha chan BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 1 7 no 0 9 0 0 0 0 1
is therefore is i is is is BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 7 - 1 9 0 0 0 0 1
sures. sures. sures. s su sur sure BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 7 . 1 1 0 0 0 0 1
Our objectives our O Ou Our Our BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 8 no 0 8 0 0 0 0 1
recurrent events recurrent r re rec recu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 -- 2 8 0 0 0 0 1
region; in region; r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 ;, 2 10 0 0 0 0 1
previously suggested previously p pr pre prev BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 - 1 8 0 0 0 0 1
pressor gene; pressor p pr pre pres BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 8 ;- 2 9 0 0 0 0 1
tern of tern t te ter tern BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 8 . 1 8 0 0 0 0 1
whole of whole w wh who whol BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 -- 2 8 0 0 0 0 1
panel of panel p pa pan pane BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 , 1 9 0 0 0 0 1
regions of regions r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 . 1 8 0 0 0 0 1
obtained SKY obtained o ob obt obta BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 no 0 9 0 0 0 0 1
lines used lines l li lin line BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 .- 2 9 0 0 0 0 1
creatic cancer creatic c cr cre crea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 8 no 0 9 0 0 0 0 1
cytogenetic cytogenetic cytogenetic c cy cyt cyto BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 8 no 0 1 0 0 0 0 1
resolution resolution resolution r re res reso BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 8 no 0 1 0 0 0 0 1
http://www.path.cam.ac.uk/ http://www.path.cam.ac.uk/ http://www.path.cam.ac.uk/ h ht htt http BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 1 1 8 ://..../ 8 4 0 0 0 0 1
~pawefish/index.html. ~pawefish/index.html. ~pawefish/index.html. ~ ~p ~pa ~paw BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 8 /.. 3 3 0 0 0 0 1
Methods Methods methods M Me Met Meth BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 10 no 0 10 0 0 0 0 1
Cell lines cell C Ce Cel Cell BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 10 no 0 5 0 0 0 0 1
Details of details D De Det Deta BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 10 no 0 10 0 0 0 0 1
1. Immortalised 1. 1 1. 1. 1. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 10 . 1 8 0 0 0 0 1
HB4a [24] hb4a H HB HB4 HB4a BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 10 []' 3 8 0 0 0 0 1
(LICR/UCL Breast (licr/ucl ( (L (LI (LIC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 1 10 (/,, 4 9 0 0 0 0 1
London, UK) london, L Lo Lon Lond BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 1 10 ,) 2 8 0 0 0 0 1
obtained from obtained o ob obt obta BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 10 -( 2 8 0 0 0 0 1
Sanger Institute, sanger S Sa San Sang BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 1 10 ,,). 4 8 0 0 0 0 1
DMEM:F12 (Invitrogen, dmem:f12 D DM DME DMEM BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 10 :(,,). 6 5 0 0 0 0 1
All tumours all A Al All All BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 11 no 0 10 0 0 0 0 1
(91% < (91% ( (9 (91 (91% BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 11 (),- 4 9 0 0 0 0 1
lected between lected l le lec lect BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 11 / 1 9 0 0 0 0 1
Tenovus series tenovus T Te Ten Teno BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 1 11 [-].. 5 9 0 0 0 0 1
microarray consisted microarray m mi mic micr BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 11 .- 2 9 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 1 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 1 0 ://../-// 9 10 0 0 1 0 1
Page 3 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 1 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 0 () 2 10 0 0 0 0 0
ing RNA, ing i in ing ing BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 1 0 ,--, 4 10 0 0 0 0 1
available for available a av ava avai BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 . 1 5 0 0 0 0 1
Array construction array A Ar Arr Arra BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 0 no 0 3 0 0 0 0 1
For the for F Fo For For BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 0 , 1 9 0 0 0 0 1
for the for f fo for for BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 no 0 10 0 0 0 0 1
available from available a av ava avai BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 (,, 3 9 0 0 0 0 1
USA) [30]. usa) U US USA USA) BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 1 0 )[]. 4 9 0 0 0 0 1
from Invitrogen from f fr fro from BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 . 1 9 0 0 0 0 1
A subset a A A A A BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 1 0 no 0 9 0 0 0 0 1
their identity. their t th the thei BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 .- 2 10 0 0 0 0 1
tion on tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 0 . 1 8 0 0 0 0 1
evidence of evidence e ev evi evid BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 no 0 9 0 0 0 0 1
substituted on substituted s su sub subs BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 . 1 9 0 0 0 0 1
BAC clones bac B BA BAC BAC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 1 0 no 0 9 0 0 0 0 1
138 kb. 138 1 13 138 138 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 1 0 . 1 9 0 0 0 0 1
actual resolution actual a ac act actu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 ., 2 9 0 0 0 0 1
123 fosmids 123 1 12 123 123 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 1 0 , 1 8 0 0 0 0 1
mainly covering mainly m ma mai main BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 .( 2 9 0 0 0 0 1
21.59 Mb 21.59 2 21 21. 21.5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 0 ..)( 4 8 0 0 0 0 1
12.97 Mb 12.97 1 12 12. 12.9 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 0 ..- 3 9 0 0 0 0 1
genic regions), genic g ge gen geni BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 0 ), 2 9 0 0 0 0 1
multiple rearrangements, multiple m mu mul mult BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 ,.. 3 8 0 0 0 0 1
BACs were bacs B BA BAC BACs BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 1 0 .[] 3 9 0 0 0 0 1
and printed and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 no 0 8 0 0 0 0 1
described in described d de des desc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 .[](- 5 9 0 0 0 0 1
sham Biosciences, sham s sh sha sham BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 ,,).- 5 8 0 0 0 0 1
pared by pared p pa par pare BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 0 . 1 9 0 0 0 0 1
Array hybridisation array A Ar Arr Arra BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 3 no 0 3 0 0 0 0 1
Array hybridisations array A Ar Arr Arra BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 3 no 0 8 0 0 0 0 1
described in described d de des desc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 3 .[].[]. 7 10 0 0 0 0 1
genomic DNA genomic g ge gen geno BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 - 1 8 0 0 0 0 1
normal female normal n no nor norm BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 3 -( 2 8 0 0 0 0 1
Biosciences) using biosciences) B Bi Bio Bios BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 1 3 )(). 4 9 0 0 0 0 1
Samples were samples S Sa Sam Samp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 1 0 0 0 0 0 1 3 - 1 9 0 0 0 0 1
ence of ence e en enc ence BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 (),/ 4 8 0 0 0 0 1
0.05% Tween-20 0.05% 0 0. 0.0 0.05 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 1 3 .-,/ 4 8 0 0 0 0 1
SSC at ssc S SS SSC SSC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 1 3 /.-. 4 8 0 0 0 0 1
Arrays were arrays A Ar Arr Arra BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 3 no 0 9 0 0 0 0 1
collected using collected c co col coll BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 3 .(- 3 8 0 0 0 0 1
ments, CA, ments, m me men ment BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 ,,).- 5 9 0 0 0 0 1
ing, chromosomes ing, i in ing ing, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 ,(, 3 7 0 0 0 0 1
University of university U Un Uni Univ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 3 ,)-- 4 9 0 0 0 0 1
etry and etry e et etr etry BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 (,- 3 8 0 0 0 0 1
inghamshire, UK) inghamshire, i in ing ingh BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 ,) 2 9 0 0 0 0 1
al. [33]. al. a al al. al. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 .[].-- 6 9 0 0 0 0 1
fied normal fied f fi fie fied BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 3 . 1 5 0 0 0 0 1
The array the T Th The The BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 1 5 -- 2 9 0 0 0 0 1
female hybridisations female f fe fem fema BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 5 - 1 8 0 0 0 0 1
ments in ments m me men ment BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 5 ().- 4 10 0 0 0 0 1
gave a gave g ga gav gave BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 5 ().- 4 9 0 0 0 0 1
hybridisation ± hybridisation h hy hyb hybr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 1 5 .. 2 10 0 0 0 0 1
copy number copy c co cop copy BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 1 5 no 0 8 0 0 0 0 1
T47D against t47d T T4 T47 T47D BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 6 . 1 7 0 0 0 0 1
changes were changes c ch cha chan BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 2 6 , 1 9 0 0 0 0 1
both the both b bo bot both BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 6 no 0 10 0 0 0 0 1
sample. In sample. s sa sam samp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 6 .. 2 9 0 0 0 0 1
was scored was w wa was was BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 6 no 0 9 0 0 0 0 1
ratio of ratio r ra rat rati BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 6 . 1 7 0 0 0 0 1
Chi-squared test chi-squared C Ch Chi Chi- BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 2 7 - 1 2 0 0 0 0 1
The probability the T Th The The BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 7 - 1 9 0 0 0 0 1
ments on ments m me men ment BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 7 no 0 9 0 0 0 0 1
pre-disposition to pre-disposition p pr pre pre- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 7 - 1 10 0 0 0 0 1
by chi-squared by b by by by BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 7 -. 2 9 0 0 0 0 1
major bands major m ma maj majo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 2 7 (,,,,) 6 8 0 0 0 0 1
number of number n nu num numb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 7 no 0 9 0 0 0 0 1
number expected number n nu num numb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 7 no 0 9 0 0 0 0 1
band. band. band. b ba ban band BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 7 . 1 1 0 0 0 0 1
Fluorescence in fluorescence F Fl Flu Fluo BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 2 8 () 2 7 0 0 0 0 1
Metaphase preparation metaphase M Me Met Meta BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 2 8 no 0 9 0 0 0 0 1
described previously described d de des desc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 [,]. 4 9 0 0 0 0 1
made using made m ma mad made BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 no 0 10 0 0 0 0 1
Patricia O'Brien patricia P Pa Pat Patr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 0 0 0 0 0 0 2 8 '-(- 4 10 0 0 0 0 1
sity of sity s si sit sity BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 8 ,). 3 9 0 0 0 0 1
tested individually tested t te tes test BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 () 2 9 0 0 0 0 1
hybridisation to hybridisation h hy hyb hybr BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 8 . 1 9 0 0 0 0 1
FISH on fish F FI FIS FISH BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 1 1 0 0 0 0 0 2 8 no 0 5 0 0 0 0 1
Tissue microarray tissue T Ti Tis Tiss BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 8 - 1 8 0 0 0 0 1
fixed paraffin fixed f fi fix fixe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 no 0 9 0 0 0 0 1
the method the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 .[]. 4 10 0 0 0 0 1
embedded tumours embedded e em emb embe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 no 0 9 0 0 0 0 1
conventional FISH. conventional c co con conv BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 .,- 3 8 0 0 0 0 1
(21.8 Mb; (21.8 ( (2 (21 (21. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 8 (.; 3 9 0 0 0 0 1
to NCBI to t to to to BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 ),-(.)- 7 8 0 0 0 0 1
70D12 (22.0 70d12 7 70 70D 70D1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 8 (.), 4 9 0 0 0 0 1
of two of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 8 ,-(.)- 6 8 0 0 0 0 1
(19.5 Mb), (19.5 ( (1 (19 (19. BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 8 (.),. 5 6 0 0 0 0 1
RT-PCR RT-PCR rt-pcr R RT RT- RT-P BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 2 10 - 1 1 0 0 0 0 1
RNA was rna R RN RNA RNA BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 2 10 no 0 9 0 0 0 0 1
Transcriptase (Invitrogen) transcriptase T Tr Tra Tran BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 2 10 ().- 4 9 0 0 0 0 1
tive real-time tive t ti tiv tive BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 10 -,, 3 10 0 0 0 0 1
reactions containing reactions r re rea reac BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 10 no 0 8 0 0 0 0 1
(Applied Biosystems, (applied ( (A (Ap (App BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 10 (,,),. 6 8 0 0 0 0 1
and reverse and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 10 - 1 8 0 0 0 0 1
diluted cDNA. diluted d di dil dilu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 10 ., 2 9 0 0 0 0 1
95°C for 95°c 9 95 95° 95°C BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 10 , 1 9 0 0 0 0 1
1 min 1 1 1 1 1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 2 10 , 1 9 0 0 0 0 1
for 15 for f fo for for BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 10 no 0 8 0 0 0 0 1
Sequence Detection sequence S Se Seq Sequ BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 10 (). 3 8 0 0 0 0 1
Primer sequences primer P Pr Pri Prim BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 11 . 1 9 0 0 0 0 1
curves for curves c cu cur curv BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 11 - 1 10 0 0 0 0 1
cation efficiency cation c ca cat cati BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 11 no 0 9 0 0 0 0 1
following qPCR following f fo fol foll BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 11 no 0 9 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 2 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 2 0 ://../-// 9 10 0 0 1 0 1
Page 4 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 2 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 0 () 2 10 0 0 0 0 0
single product. single s si sin sing BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 0 . 1 10 0 0 0 0 1
as: as: as: a as as: as: BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 0 : 1 0 0 0 0 0 1
For primary for F Fo For For BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 0 no 0 9 0 0 0 0 1
the median-expressing the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 0 -., 3 9 0 0 0 0 1
purified basal purified p pu pur puri BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 0 [](- 4 10 0 0 0 0 1
sor Mike sor s so sor sor BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 0 ',,), 5 9 0 0 0 0 1
normal RNAs normal n no nor norm BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 0 ((,), 5 9 0 0 0 0 1
(Europa Bioproducts (europa ( (E (Eu (Eur BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 0 (,,), 5 7 0 0 0 0 1
(Huntingdon, UK), (huntingdon, ( (H (Hu (Hun BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 0 (,),(, 6 8 0 0 0 0 1
Abingdon, UK), abingdon, A Ab Abi Abin BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 2 0 ,),(,)),- 9 8 0 0 0 0 1
mal breast mal m ma mal mal BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 0 . 1 8 0 0 0 0 1
Results Results results R Re Res Resu BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 2 1 no 0 10 0 0 0 0 1
Array CGH array A Ar Arr Arra BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 1 no 0 9 0 0 0 0 1
six pancreatic six s si six six BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 (, 2 10 0 0 0 0 1
4). Five 4). 4 4) 4). 4). BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 1 ). 2 10 0 0 0 0 1
8q, five 8q, 8 8q 8q, 8q, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 1 ,, 2 8 0 0 0 0 1
remaining 28 remaining r re rem rema BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 no 0 9 0 0 0 0 1
(Additional file (additional ( (A (Ad (Add BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 1 ().-- 5 9 0 0 0 0 1
tion of tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 1 no 0 8 0 0 0 0 1
bands was bands b ba ban band BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 -(.),- 6 9 0 0 0 0 1
rangements of rangements r ra ran rang BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 1 no 0 8 0 0 0 0 1
breaks occur breaks b br bre brea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 -- 2 7 0 0 0 0 1
regions. We regions. r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 .,- 3 9 0 0 0 0 1
location breakpoints location l lo loc loca BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 -(. 3 8 0 0 0 0 1
– centromere), – – – – – BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 2 1 –),- 4 9 0 0 0 0 1
rangement (Figure rangement r ra ran rang BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 1 (). 3 9 0 0 0 0 1
8p: two 8p: 8 8p 8p: 8p: BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 1 :, 2 9 0 0 0 0 1
novel region novel n no nov nove BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 .(.–. 5 9 0 0 0 0 1
Mb), a mb), M Mb Mb) Mb), BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 2 1 ),(. 4 9 0 0 0 0 1
Mb – mb M Mb Mb Mb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 2 1 –.) 3 8 0 0 0 0 1
8p23.3 (0 8p23.3 8 8p 8p2 8p23 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 1 .(–.). 6 9 0 0 0 0 1
of candidate of o of of of BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 1 . 1 9 0 0 0 0 1
Normal copy normal N No Nor Norm BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 3 no 0 8 0 0 0 0 1
around 7 around a ar aro arou BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 3 .,- 3 10 0 0 0 0 1
mental duplication mental m me men ment BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 3 no 0 8 0 0 0 0 1
highly polymorphic highly h hi hig high BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 3 ,[,]. 5 9 0 0 0 0 1
with BACs with w wi wit with BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 3 -(.; 4 9 0 0 0 0 1
BAC midpoints bac B BA BAC BAC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 2 3 )- 2 8 0 0 0 0 1
43B8 (7.76 43b8 4 43 43B 43B8 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 3 (.)- 4 9 0 0 0 0 1
toid interphase toid t to toi toid BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 3 no 0 9 0 0 0 0 1
were present were w we wer were BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 3 no 0 8 0 0 0 0 1
(Additional file (additional ( (A (Ad (Add BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 3 (). 3 3 0 0 0 0 1
8p11-12 amplicon 8p11-12 8 8p 8p1 8p11 BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 4 - 1 2 0 0 0 0 1
As we as A As As As BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 4 ,(/) 4 9 0 0 0 0 1
with rearrangements with w wi wit with BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 4 no 0 8 0 0 0 0 1
step in step s st ste step BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 4 -, 2 10 0 0 0 0 1
region. Similarly, region. r re reg regi BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 4 ., 2 8 0 0 0 0 1
were in were w we wer were BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 -. 2 9 0 0 0 0 1
full analysis full f fu ful full BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 .[]. 4 10 0 0 0 0 1
A novel a A A A A BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 2 5 . 1 4 0 0 0 0 1
Two cell two T Tw Two Two BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 2 5 ,---,- 6 8 0 0 0 0 1
cation in cation c ca cat cati BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 5 ..- 3 9 0 0 0 0 1
firmed and firmed f fi fir firm BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 5 no 0 9 0 0 0 0 1
CGH (Figures cgh C CG CGH CGH BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 2 5 (,).- 5 9 0 0 0 0 1
cons contained cons c co con cons BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 ( 1 8 0 0 0 0 1
Alpha-2) (21.6 alpha-2) A Al Alp Alph BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 5 -)(.),()(.), 12 9 0 0 0 0 1
XPO7 (exportin xpo7 X XP XPO XPO7 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 2 5 ()(.),(/- 9 9 0 0 0 0 1
oplasmin family oplasmin o op opl opla BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 5 )(.)(- 6 9 0 0 0 0 1
last Growth last l la las last BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 )(.). 5 9 0 0 0 0 1
the amplicon the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 -- 2 8 0 0 0 0 1
(Erythrocyte membrane (erythrocyte ( (E (Er (Ery BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 2 5 ()(.), 6 8 0 0 0 0 1
whereas the whereas w wh whe wher BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 - 1 8 0 0 0 0 1
encompass up encompass e en enc enco BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 no 0 9 0 0 0 0 1
RNA. By rna. R RN RNA RNA. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 2 5 ., 2 8 0 0 0 0 1
in BT-20 in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 2 5 - 1 9 0 0 0 0 1
step up step s st ste step BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 .(), 4 10 0 0 0 0 1
of BT-20 of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 ---- 4 8 0 0 0 0 1
con. con. con. c co con con. BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 2 5 . 1 0 0 0 0 0 1
FISH was fish F FI FIS FISH BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 1 1 0 0 0 0 0 3 8 no 0 9 0 0 0 0 1
investigate their investigate i in inv inve BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 8 .-- 3 10 0 0 0 0 1
235B11 (23.0 235b11 2 23 235 235B BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 8 (.),- 5 9 0 0 0 0 1
tion, and tion, t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 8 ,-(.),- 7 8 0 0 0 0 1
cent region cent c ce cen cent BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 8 , 1 10 0 0 0 0 1
copy number copy c co cop copy BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 8 -(). 4 9 0 0 0 0 1
There was there T Th The Ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 8 - 1 9 0 0 0 0 1
nals from nals n na nal nals BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 8 . 1 9 0 0 0 0 1
highest amplification highest h hi hig high BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 8 - 1 10 0 0 0 0 1
ative chromosome. ative a at ati ativ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 8 . 1 8 0 0 0 0 1
amplification was amplification a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 8 no 0 9 0 0 0 0 1
copy was copy c co cop copy BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 8 . 1 9 0 0 0 0 1
MDA-MB-134 is mda-mb-134 M MD MDA MDA- BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 -- 2 8 0 0 0 0 1
part of part p pa par part BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 - 1 9 0 0 0 0 1
and 11 and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 [].-- 5 9 0 0 0 0 1
out with out o ou out out BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 -(.),. 6 8 0 0 0 0 1
amplicon, and amplicon, a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 9 ,-(.) 5 8 0 0 0 0 1
8p12 amplicon. 8p12 8 8p 8p1 8p12 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 .. 2 8 0 0 0 0 1
was intermingled was w wa was was BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 no 0 9 0 0 0 0 1
the der(?)t(8;11)ins(8;11) the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 (?)(;)(;)()., 13 10 0 0 0 0 1
also showed also a al als also BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 - 1 9 0 0 0 0 1
some are some s so som some BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 - 1 9 0 0 0 0 1
tion since tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 9 . 1 9 0 0 0 0 1
apparently normal apparently a ap app appa BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 9 . 1 6 0 0 0 0 1
Dramatic amplification dramatic D Dr Dra Dram BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 10 no 0 10 0 0 0 0 1
in BT-20 in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 3 10 --- 3 8 0 0 0 0 1
single primary single s si sin sing BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 10 , 1 9 0 0 0 0 1
cores, by cores, c co cor core BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 10 ,- 2 9 0 0 0 0 1
ray, with ray, r ra ray ray, BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 10 , 1 9 0 0 0 0 1
Average Sample average A Av Ave Aver BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 11 no 0 10 0 0 0 0 1
− − − − − − − BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 3 11 − 1 0 0 0 0 0 1
( ( ( ( ( ( ( BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 3 11 (( 2 1 0 0 0 0 1
) Amplification ) ) ) ) ) BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 3 11 ) 1 10 0 0 0 0 1
Average Sample average A Av Ave Aver BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 11 no 0 10 0 0 0 0 1
Amplification Co amplification A Am Amp Ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 11 no 0 2 0 0 0 0 1
− − − − − − − BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 3 11 − 1 0 0 0 0 0 1
( ( ( ( ( ( ( BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 3 11 ( 1 10 0 0 0 0 1
) ) ) ) ) ) ) BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 3 11 ) 1 10 0 0 0 0 1
e efficient e e e e e BLOCKSTART PAGEEND NEWFONT LOWERFONT 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 3 11 no 0 10 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT HIGHERFONT 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 3 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 3 0 ://../-// 9 10 0 0 1 0 1
Page 5 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 3 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 0 () 2 10 0 0 0 0 0
(21.8 Mb-22.1 (21.8 ( (2 (21 (21. BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 0 (.-.). 6 10 0 0 0 0 1
to the to t to to to BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 0 (.-.)(). 8 8 0 0 0 0 1
Expression of expression E Ex Exp Expr BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 1 ,, 2 9 0 0 0 0 1
XPO7, NPM2, xpo7, X XP XPO XPO7 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 1 ,,, 3 9 0 0 0 0 1
amplification had amplification a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 1 .- 2 10 0 0 0 0 1
tative RT-PCR tative t ta tat tati BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 1 - 1 9 0 0 0 0 1
lines that lines l li lin line BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 2 , 1 10 0 0 0 0 1
without amplification without w wi wit with BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 2 (). 3 9 0 0 0 0 1
was excluded was w wa was was BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 2 no 0 8 0 0 0 0 1
expression was expression e ex exp expr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 2 no 0 8 0 0 0 0 1
normal breast normal n no nor norm BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 2 ,---( 5 9 0 0 0 0 1
not shown). not n no not not BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 2 ).--- 5 8 0 0 0 0 1
GFRA2, XPO7, gfra2, G GF GFR GFRA BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 2 ,, 2 8 0 0 0 0 1
Array CGH array A Ar Arr Arra BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 3 no 0 3 0 0 0 0 1
Figure 1 figure F Fi Fig Figu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 3 no 0 0 0 0 0 0 1
Array CGH array A Ar Arr Arra BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 3 . 1 8 0 0 0 0 1
chromosome bands chromosome c ch chr chro BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 3 no 0 9 0 0 0 0 1
ideogram. Previously ideogram. i id ide ideo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 3 .(-). 5 9 0 0 0 0 1
regions identified regions r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 3 . 1 9 0 0 0 0 1
in 8p23.3, in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 3 3 .,/. 4 9 0 0 0 0 1
including gain, including i in inc incl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 3 ,.(:// 6 9 0 0 0 0 1
acgh.afcri.upenn.edu, [64]). acgh.afcri.upenn.edu, a ac acg acgh BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 3 ...,[]).-, 10 9 0 0 0 0 1
loss and loss l lo los loss BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 3 .. 2 9 0 0 0 0 1
show no show s sh sho show BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 3 ., 2 9 0 0 0 0 1
ploidy of ploidy p pl plo ploi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 3 ;,;,;,;,;* 10 10 0 0 0 0 1
pancreatic line. pancreatic p pa pan panc BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 3 . 1 1 0 0 0 0 1
p11 p11 p11 p p1 p11 p11 BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 8 no 0 10 0 0 0 0 1
p12 p12 p12 p p1 p12 p12 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 8 no 0 10 0 0 0 0 1
p22 p22 p22 p p2 p22 p22 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 8 no 0 10 0 0 0 0 1
p21.3 p21.3 p21.3 p p2 p21 p21. BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
p21.2 p21.2 p21.2 p p2 p21 p21. BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
p21.1 p21.1 p21.1 p p2 p21 p21. BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
p23.1 p23.1 p23.1 p p2 p23 p23. BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
p23.2 p23.2 p23.2 p p2 p23 p23. BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
p23.3 p23.3 p23.3 p p2 p23 p23. BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
19.1Mb 19.1Mb 19.1mb 1 19 19. 19.1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
2.2Mb 2.2Mb 2.2mb 2 2. 2.2 2.2M BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
6.2Mb 6.2Mb 6.2mb 6 6. 6.2 6.2M BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
12.7Mb 12.7Mb 12.7mb 1 12 12. 12.7 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
23.4Mb 23.4Mb 23.4mb 2 23 23. 23.4 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
27.4Mb 27.4Mb 27.4mb 2 27 27. 27.4 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
29.7Mb 29.7Mb 29.7mb 2 29 29. 29.7 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
38.5Mb 38.5Mb 38.5mb 3 38 38. 38.5 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
43.8Mb 43.8Mb 43.8mb 4 43 43. 43.8 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 9 . 1 10 0 0 0 0 1
Telomere Telomere telomere T Te Tel Telo BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 3 9 no 0 10 0 0 0 0 1
Centromere Centromere centromere C Ce Cen Cent BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 3 9 no 0 10 0 0 0 0 1
ZR-75-1 ZR-75-1 zr-75-1 Z ZR ZR- ZR-7 BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 -- 2 10 0 0 0 0 1
SUM52 SUM52 sum52 S SU SUM SUM5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 no 0 7 0 0 0 0 1
HCC1806 HCC1806 hcc1806 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 10 no 0 10 0 0 0 0 1
*PaTu-1 *PaTu-1 *patu-1 * *P *Pa *PaT BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 *- 2 10 0 0 0 0 1
HCC1569 HCC1569 hcc1569 H HC HCC HCC1 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 10 no 0 10 0 0 0 0 1
* SUIT2 * * * * * BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 3 10 * 1 10 0 0 0 0 1
T47D T47D t47d T T4 T47 T47D BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 no 0 4 0 0 0 0 1
*CF-PAC-1 *CF-PAC-1 *cf-pac-1 * *C *CF *CF- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 *-- 3 9 0 0 0 0 1
MDA-MB-361 MDA-MB-361 mda-mb-361 M MD MDA MDA- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 -- 2 10 0 0 0 0 1
HCC38 HCC38 hcc38 H HC HCC HCC3 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 no 0 5 0 0 0 0 1
MDA-MB-134 MDA-MB-134 mda-mb-134 M MD MDA MDA- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 -- 2 10 0 0 0 0 1
CaMa-1 CaMa-1 cama-1 C Ca CaM CaMa BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 - 1 6 0 0 0 0 1
HCC1500 HCC1500 hcc1500 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 10 no 0 7 0 0 0 0 1
HCC1143 HCC1143 hcc1143 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 10 no 0 7 0 0 0 0 1
SUM44 SUM44 sum44 S SU SUM SUM4 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 no 0 5 0 0 0 0 1
MDA-MB-453 MDA-MB-453 mda-mb-453 M MD MDA MDA- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 -- 2 10 0 0 0 0 1
*Capan-1 *Capan-1 *capan-1 * *C *Ca *Cap BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 *- 2 8 0 0 0 0 1
HCC1599 HCC1599 hcc1599 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 10 no 0 7 0 0 0 0 1
UACC-812 UACC-812 uacc-812 U UA UAC UACC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 - 1 8 0 0 0 0 1
*Rwp-1 *Rwp-1 *rwp-1 * *R *Rw *Rwp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 *- 2 6 0 0 0 0 1
ZR-75-30 ZR-75-30 zr-75-30 Z ZR ZR- ZR-7 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 -- 2 8 0 0 0 0 1
HCC1954 HCC1954 hcc1954 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 10 no 0 7 0 0 0 0 1
HCC1937 HCC1937 hcc1937 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 10 no 0 7 0 0 0 0 1
BT-20 BT-20 bt-20 B BT BT- BT-2 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 10 - 1 5 0 0 0 0 1
*MIA PaCa-2 *mia * *M *MI *MIA BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 3 11 *- 2 10 0 0 0 0 1
DU4475 DU4475 du4475 D DU DU4 DU44 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 no 0 5 0 0 0 0 1
BT-474 BT-474 bt-474 B BT BT- BT-4 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 - 1 5 0 0 0 0 1
HCC1419 HCC1419 hcc1419 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 11 no 0 6 0 0 0 0 1
Hs578t Hs578t hs578t H Hs Hs5 Hs57 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 no 0 5 0 0 0 0 1
MDA-MB-175 MDA-MB-175 mda-mb-175 M MD MDA MDA- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 -- 2 9 0 0 0 0 1
PMC42 PMC42 pmc42 P PM PMC PMC4 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 no 0 5 0 0 0 0 1
MDA-MB-468 MDA-MB-468 mda-mb-468 M MD MDA MDA- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 -- 2 9 0 0 0 0 1
MCF-7 MCF-7 mcf-7 M MC MCF MCF- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 - 1 5 0 0 0 0 1
SK-BR-3 SK-BR-3 sk-br-3 S SK SK- SK-B BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 -- 2 6 0 0 0 0 1
HCC1187 HCC1187 hcc1187 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 3 11 no 0 6 0 0 0 0 1
SUM159 SUM159 sum159 S SU SUM SUM1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 no 0 5 0 0 0 0 1
HCC70 HCC70 hcc70 H HC HCC HCC7 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 no 0 5 0 0 0 0 1
MDA-MB-415 MDA-MB-415 mda-mb-415 M MD MDA MDA- BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 11 -- 2 9 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT HIGHERFONT 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 3 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 3 0 ://../-// 9 10 0 0 1 0 1
Page 6 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 3 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 0 () 2 10 0 0 0 0 0
Analysis of analysis A An Ana Anal BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 0 . 1 2 0 0 0 0 1
Figure 2 figure F Fi Fig Figu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 0 no 0 0 0 0 0 0 1
Analysis of analysis A An Ana Anal BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 3 0 ..()().--- 10 8 0 0 0 0 1
134 respectively. 134 1 13 134 134 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 3 0 .()--(.;- 9 9 0 0 0 0 1
points on points p po poi poin BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 0 )-(.).()--- 11 8 0 0 0 0 1
458H21 (21.28 458h21 4 45 458 458H BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 0 (.)-(.). 8 9 0 0 0 0 1
but extended but b bu but but BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 0 -..- 4 9 0 0 0 0 1
sity is sity s si sit sity BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 0 .,;,.()- 8 9 0 0 0 0 1
taining material taining t ta tai tain BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 0 .-.,;,-(.);,- 13 9 0 0 0 0 1
235B11 (22.38 235b11 2 23 235 235B BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 0 (.).().-- 9 9 0 0 0 0 1
134. Blue, 134. 1 13 134 134. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 3 0 .,;,-(.);,-(.).(). 18 9 0 0 0 0 1
amplicon on amplicon a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 0 .,(.); 6 9 0 0 0 0 1
(also indicated (also ( (a (al (als BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 0 (),(.);,.() 11 9 0 0 0 0 1
the five the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 0 ---,-- 6 9 0 0 0 0 1
compared to compared c co com comp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 0 .() 3 9 0 0 0 0 1
(h) NPM2 (h) ( (h (h) (h) BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 3 0 ().,;,( 7 9 0 0 0 0 1
more than more m mo mor more BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 0 .-);,(- 7 10 0 0 0 0 1
above the above a ab abo abov BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 3 0 ). 2 2 0 0 0 0 1
XPO7 XPO7 xpo7 X XP XPO XPO7 BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 8 no 0 8 0 0 0 0 1
DOK2 DOK2 dok2 D DO DOK DOK2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 8 no 0 8 0 0 0 0 1
GFRA2 GFRA2 gfra2 G GF GFR GFRA BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 8 no 0 10 0 0 0 0 1
-1 -1 -1 - -1 -1 -1 BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 - 1 10 0 0 0 0 1
0 0 0 0 0 0 0 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
1 1 1 1 1 1 1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
2 2 2 2 2 2 2 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
21 Mb 21 2 21 21 21 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 9 no 0 7 0 0 0 0 1
21.5 Mb 21.5 2 21 21. 21.5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 . 1 10 0 0 0 0 1
22 Mb 22 2 22 22 22 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 9 no 0 7 0 0 0 0 1
22.5 Mb 22.5 2 22 22. 22.5 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 . 1 10 0 0 0 0 1
-1 -1 -1 - -1 -1 -1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 - 1 10 0 0 0 0 1
0 0 0 0 0 0 0 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
1 1 1 1 1 1 1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
2 2 2 2 2 2 2 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
3 3 3 3 3 3 3 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
21 Mb 21 2 21 21 21 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 9 no 0 7 0 0 0 0 1
21.5 Mb 21.5 2 21 21. 21.5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 . 1 10 0 0 0 0 1
22 Mb 22 2 22 22 22 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 9 no 0 7 0 0 0 0 1
22.5 Mb 22.5 2 22 22. 22.5 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 . 1 10 0 0 0 0 1
NPM2 NPM2 npm2 N NP NPM NPM2 BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 no 0 8 0 0 0 0 1
FGF17 FGF17 fgf17 F FG FGF FGF1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
EPB49 EPB49 epb49 E EP EPB EPB4 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 9 no 0 10 0 0 0 0 1
0.01 0.01 0.01 0 0. 0.0 0.01 BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 . 1 10 0 0 0 0 1
0.1 0.1 0.1 0 0. 0.1 0.1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 . 1 10 0 0 0 0 1
1 1 1 1 1 1 1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
10 10 10 1 10 10 10 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
100 100 100 1 10 100 100 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
MDA-MB- MDA-MB- mda-mb- M MD MDA MDA- BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 4 10 -- 2 10 0 0 0 0 1
134 134 134 1 13 134 134 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 10 no 0 5 0 0 0 0 1
BT-20 DU4475 bt-20 B BT BT- BT-2 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 -- 2 10 0 0 0 0 1
GFRA2 GFRA2 gfra2 G GF GFR GFRA BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
XPO7 XPO7 xpo7 X XP XPO XPO7 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 no 0 8 0 0 0 0 1
NPM2 NPM2 npm2 N NP NPM NPM2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 no 0 8 0 0 0 0 1
FGF17 FGF17 fgf17 F FG FGF FGF1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
EBP49 EBP49 ebp49 E EB EBP EBP4 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
Fold expression fold F Fo Fol Fold BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
0.1 0.1 0.1 0 0. 0.1 0.1 BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 10 . 1 10 0 0 0 0 1
Tumours Luminal tumours T Tu Tum Tumo BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 10 no 0 10 0 0 0 0 1
Fold expression fold F Fo Fol Fold BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 10 no 0 4 0 0 0 0 1
10 10 10 1 10 10 10 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
1 1 1 1 1 1 1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
0.1 0.1 0.1 0 0. 0.1 0.1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 11 . 1 10 0 0 0 0 1
100 100 100 1 10 100 100 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
1000 1000 1000 1 10 100 1000 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 1 0 0 0 4 11 no 0 10 0 0 0 0 1
Tumours Luminal tumours T Tu Tum Tumo BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
Fold expression fold F Fo Fol Fold BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 11 no 0 4 0 0 0 0 1
a a a a a a a BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 NOCAPS NODIGIT 1 0 1 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
b b b b b b b BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
c c c c c c c BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
d d d d d d d BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
e e e e e e e BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
f f f f f f f BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
g g g g g g g BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
h h h h h h h BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
XPO7 XPO7 xpo7 X XP XPO XPO7 BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 11 no 0 8 0 0 0 0 1
DOK2 DOK2 dok2 D DO DOK DOK2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 11 no 0 8 0 0 0 0 1
GFRA2 GFRA2 gfra2 G GF GFR GFRA BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
NPM2 NPM2 npm2 N NP NPM NPM2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 11 no 0 8 0 0 0 0 1
FGF17 FGF17 fgf17 F FG FGF FGF1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
EPB49 EPB49 epb49 E EP EPB EPB4 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
1 1 1 1 1 1 1 BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
10 10 10 1 10 10 10 BLOCKSTART PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 4 11 no 0 10 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT HIGHERFONT 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 4 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 4 0 ://../-// 9 10 0 0 1 0 1
Page 7 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 4 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 0 () 2 10 0 0 0 0 0
0.5-fold expression 0.5-fold 0 0. 0.5 0.5- BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 0 .-, 3 10 0 0 0 0 1
the amplicon the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 0 ().- 4 9 0 0 0 0 1
showed marginal, showed s sh sho show BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 0 ,-,- 4 9 0 0 0 0 1
and EPB49. and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 0 .,,, 4 9 0 0 0 0 1
huge over-expression huge h hu hug huge BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 0 - 1 9 0 0 0 0 1
of amplification of o of of of BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 0 (). 3 5 0 0 0 0 1
Since NPM2 since S Si Sin Sinc BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 1 - 1 9 0 0 0 0 1
cell lines, cell c ce cel cell BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 , 1 9 0 0 0 0 1
tumours, from tumours, t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 , 1 9 0 0 0 0 1
by FISH, by b by by by BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 ,( 2 9 0 0 0 0 1
2h). However, 2h). 2 2h 2h) 2h). BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 1 )., 3 9 0 0 0 0 1
showed 8p21.3 showed s sh sho show BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 .., 3 8 0 0 0 0 1
cDNA made cdna c cD cDN cDNA BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 1 no 0 8 0 0 0 0 1
showed extreme showed s sh sho show BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 –-– 3 9 0 0 0 0 1
expression across expression e ex exp expr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 , 1 9 0 0 0 0 1
of identifying of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 no 0 8 0 0 0 0 1
tumour samples. tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 .- 2 8 0 0 0 0 1
mal samples mal m ma mal mal BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 1 no 0 8 0 0 0 0 1
obtained, for obtained, o ob obt obta BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 , 1 9 0 0 0 0 1
obtained after obtained o ob obt obta BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 no 0 8 0 0 0 0 1
representative of representative r re rep repr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 . 1 10 0 0 0 0 1
technical concerns technical t te tec tech BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 no 0 9 0 0 0 0 1
available normal available a av ava avai BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 .- 2 9 0 0 0 0 1
nal and nal n na nal nal BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 1 [] 2 10 0 0 0 0 1
and tended and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 1 - 1 9 0 0 0 0 1
els. els. els. e el els els. BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 1 . 1 0 0 0 0 0 1
None of none N No Non None BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 3 no 0 9 0 0 0 0 1
the control the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 (). 3 9 0 0 0 0 1
NPM2 at npm2 N NP NPM NPM2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 3 - 1 9 0 0 0 0 1
trols, although trols, t tr tro trol BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 3 , 1 9 0 0 0 0 1
and basal and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 (). 3 9 0 0 0 0 1
express either express e ex exp expr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 , 1 10 0 0 0 0 1
there are there t th the ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 /, 2 9 0 0 0 0 1
which have which w wh whi whic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 no 0 10 0 0 0 0 1
the rest the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 (). 3 9 0 0 0 0 1
variability of variability v va var vari BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 no 0 9 0 0 0 0 1
observation may observation o ob obs obse BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 3 -- 2 9 0 0 0 0 1
ing both ing i in ing ing BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 4 3 . 1 6 0 0 0 0 1
8p22 rearrangements 8p22 8 8p 8p2 8p22 BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 4 no 0 3 0 0 0 0 1
A cluster a A A A A BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 4 4 - 1 9 0 0 0 0 1
mon target mon m mo mon mon BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 4 .. 2 8 0 0 0 0 1
Mb in mb M Mb Mb Mb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 4 4 (,). 4 9 0 0 0 0 1
changes in changes c ch cha chan BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 4 4 : 1 9 0 0 0 0 1
HCC1806, SUM44, hcc1806, H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 4 4 ,,, 3 8 0 0 0 0 1
PaCa-2, which paca-2, P Pa PaC PaCa BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 4 -, 2 8 0 0 0 0 1
reported by reported r re rep repo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 4 .([]., 6 10 0 0 0 0 1
found a found f fo fou foun BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 4 . 1 10 0 0 0 0 1
HCC1187 by hcc1187 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 4 4 ,..- 4 9 0 0 0 0 1
ual chromosomes ual u ua ual ual BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 4 []().- 6 9 0 0 0 0 1
rangements were rangements r ra ran rang BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 4 4 -., 3 9 0 0 0 0 1
by array by b by by by BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 4 no 0 9 0 0 0 0 1
in this in i in in in BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 4 4 ,.-.(),.-. 10 9 0 0 0 0 1
Mb (SGCZ mb M Mb Mb Mb BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 4 6 (–).-. 6 10 0 0 0 0 1
(TUSC3) (Figure (tusc3) ( (T (TU (TUS BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 6 ()(,). 6 8 0 0 0 0 1
In SUM44 in I In In In BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 4 6 no 0 9 0 0 0 0 1
an extra an a an an an BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 4 6 no 0 10 0 0 0 0 1
13.6 Mb, 13.6 1 13 13. 13.6 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 6 ., 2 8 0 0 0 0 1
array CGH, array a ar arr arra BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 6 ,.,. 4 8 0 0 0 0 1
deletion between deletion d de del dele BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 6 .., 3 8 0 0 0 0 1
same region same s sa sam same BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 6 -. 2 9 0 0 0 0 1
The copy the T Th The The BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 4 6 no 0 9 0 0 0 0 1
small and small s sm sma smal BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 4 6 ,-(.) 5 7 0 0 0 0 1
within the within w wi wit with BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 6 -(.) 4 8 0 0 0 0 1
just outside just j ju jus just BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 6 , 1 10 0 0 0 0 1
on one on o on on on BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 4 6 no 0 9 0 0 0 0 1
DU4475 cells du4475 D DU DU4 DU44 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 4 6 (). 3 4 0 0 0 0 1
In HCC1806 in I In In In BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 5 7 no 0 8 0 0 0 0 1
(Figure 3a). (figure ( (F (Fi (Fig BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 7 ().[] 5 10 0 0 0 0 1
BAC array bac B BA BAC BAC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 5 7 no 0 9 0 0 0 0 1
copies of copies c co cop copi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 7 . 1 8 0 0 0 0 1
between 12.6 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 7 .., 3 9 0 0 0 0 1
cancer gene cancer c ca can canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 7 ,- 2 9 0 0 0 0 1
mosome 8, mosome m mo mos moso BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 7 , 1 8 0 0 0 0 1
between 14.2 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 7 ..()(-). 8 8 0 0 0 0 1
Hybridisation of hybridisation H Hy Hyb Hybr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 5 7 -()(-)- 7 9 0 0 0 0 1
mid array mid m mi mid mid BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 7 no 0 9 0 0 0 0 1
between 14.19 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 7 .., 3 8 0 0 0 0 1
(Figure 3a). (figure ( (F (Fi (Fig BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 7 (). 3 2 0 0 0 0 1
Overall DLC1, overall O Ov Ove Over BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 9 ,- 2 8 0 0 0 0 1
pressor candidate pressor p pr pre pres BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 9 , 1 9 0 0 0 0 1
cell line cell c ce cel cell BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 9 no 0 9 0 0 0 0 1
other genes. other o ot oth othe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 9 . 1 10 0 0 0 0 1
known that known k kn kno know BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 9 no 0 9 0 0 0 0 1
number [39] number n nu num numb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 9 [],,-- 6 9 0 0 0 0 1
tion is tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 9 []. 3 9 0 0 0 0 1
of this, of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 9 ,(/) 4 9 0 0 0 0 1
lines analysed lines l li lin line BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 9 , 1 9 0 0 0 0 1
without detectable without w wi wit with BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 9 ( 1 9 0 0 0 0 1
3c). 3c). 3c). 3 3c 3c) 3c). BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 9 ). 2 0 0 0 0 0 1
In contrast, in I In In In BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 5 10 , 1 9 0 0 0 0 1
that did that t th tha that BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 10 . 1 8 0 0 0 0 1
decreased expression decreased d de dec decr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 10 no 0 10 0 0 0 0 1
not in not n no not not BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 10 ()., 4 10 0 0 0 0 1
showed decreased showed s sh sho show BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 10 no 0 8 0 0 0 0 1
breast tumours breast b br bre brea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 10 (). 3 9 0 0 0 0 1
that had that t th tha that BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 10 ,- 2 9 0 0 0 0 1
ther thirteen ther t th the ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 10 no 0 9 0 0 0 0 1
range observed range r ra ran rang BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 10 . 1 9 0 0 0 0 1
Neither the neither N Ne Nei Neit BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 11 '' 2 9 0 0 0 0 1
in the in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 5 11 no 0 7 0 0 0 0 1
(HCC1187, SUM44), (hcc1187, ( (H (HC (HCC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 5 11 (,), 4 8 0 0 0 0 1
(results not (results ( (r (re (res BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 11 (),- 4 10 0 0 0 0 1
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Analysis of analysis A An Ana Anal BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 1 no 0 2 0 0 0 0 1
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number for number n nu num numb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 1 ;,;,;, 6 9 0 0 0 0 1
reciprocal translocation; reciprocal r re rec reci BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 1 ;,.() 5 10 0 0 0 0 1
of chromosome of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 1 .,;,-(.);,-(.).() 17 9 0 0 0 0 1
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SGCZ SGCZ sgcz S SG SGC SGCZ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 5 9 no 0 8 0 0 0 0 1
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SUM44 SUM44 sum44 S SU SUM SUM4 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 9 no 0 10 0 0 0 0 1
MIA Pa mia M MI MIA MIA BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 1 0 0 0 0 0 0 5 9 - 1 10 0 0 0 0 1
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DU4475 DU4475 du4475 D DU DU4 DU44 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 9 no 0 10 0 0 0 0 1
8p22 8p22 8p22 8 8p 8p2 8p22 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 10 no 0 10 0 0 0 0 1
Fold expression fold F Fo Fol Fold BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 10 no 0 10 0 0 0 0 1
10 10 10 1 10 10 10 BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 NOCAPS ALLDIGIT 0 0 0 0 0 0 0 0 5 10 no 0 10 0 0 0 0 1
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Fold expression fold F Fo Fol Fold BLOCKSTART PAGEIN SAMEFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 10 no 0 10 0 0 0 0 1
c c c c c c c BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 5 10 no 0 10 0 0 0 0 1
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MIA PaCa-2 mia M MI MIA MIA BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 1 0 0 0 0 0 0 5 10 - 1 10 0 0 0 0 1
SUM44 SUM44 sum44 S SU SUM SUM4 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 11 no 0 5 0 0 0 0 1
HCC1187 HCC1187 hcc1187 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 5 11 no 0 7 0 0 0 0 1
HCC1806 HCC1806 hcc1806 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 5 11 no 0 7 0 0 0 0 1
BT-20 BT-20 bt-20 B BT BT- BT-2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 11 - 1 5 0 0 0 0 1
HCC1569 HCC1569 hcc1569 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 5 11 no 0 7 0 0 0 0 1
SK-BR-3 SK-BR-3 sk-br-3 S SK SK- SK-B BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 11 -- 2 7 0 0 0 0 1
MCF-7 MCF-7 mcf-7 M MC MCF MCF- BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 11 - 1 5 0 0 0 0 1
HCC1500 HCC1500 hcc1500 H HC HCC HCC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 5 11 no 0 7 0 0 0 0 1
HCC38 HCC38 hcc38 H HC HCC HCC3 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 11 no 0 5 0 0 0 0 1
PMC42 PMC42 pmc42 P PM PMC PMC4 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 11 no 0 5 0 0 0 0 1
MDA-MB-134 MDA-MB-134 mda-mb-134 M MD MDA MDA- BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 11 -- 2 10 0 0 0 0 1
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http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 5 0 ://../-// 9 10 0 0 1 0 1
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(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 0 () 2 10 0 0 0 0 0
tion nor tion t ti tio tion BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 0 no 0 10 0 0 0 0 1
or insertion or o or or or BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 0 . 1 4 0 0 0 0 1
Loss of loss L Lo Los Loss BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 0 . 1 2 0 0 0 0 1
Six cell six S Si Six Six BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 0 , 1 10 0 0 0 0 1
8p23, all 8p23, 8 8p 8p2 8p23 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 0 ,- 2 8 0 0 0 0 1
tion from tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 0 ..()., 6 8 0 0 0 0 1
and HCC1569 and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 0 ., 2 8 0 0 0 0 1
3.4 Mb 3.4 3 3. 3.4 3.4 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 0 ..; 3 9 0 0 0 0 1
between 1.3 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 0 ..;- 4 8 0 0 0 0 1
zygous deletion zygous z zy zyg zygo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 0 .. 2 8 0 0 0 0 1
PaCa-2 had paca-2 P Pa PaC PaCa BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 0 -. 2 8 0 0 0 0 1
1.9 Mb, 1.9 1 1. 1.9 1.9 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 0 .,.([]. 7 10 0 0 0 0 1
identify the identify i id ide iden BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 0 no 0 8 0 0 0 0 1
region of region r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 0 ,- 2 9 0 0 0 0 1
was mapped was w wa was was BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 0 ., 2 9 0 0 0 0 1
2 of 2 2 2 2 2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 5 0 ,, 2 9 0 0 0 0 1
hsa-mir-596 (Figure hsa-mir-596 h hs hsa hsa- BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 0 --(). 5 4 0 0 0 0 1
Since DU4475 since S Si Sin Sinc BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 2 , 1 9 0 0 0 0 1
the classical the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 , 1 8 0 0 0 0 1
would expect would w wo wou woul BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 no 0 9 0 0 0 0 1
disrupted by disrupted d di dis disr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 ,- 2 8 0 0 0 0 1
tion, in tion, t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 2 ,. 2 10 0 0 0 0 1
lines (not lines l li lin line BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 () 2 8 0 0 0 0 1
target gene target t ta tar targ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 , 1 8 0 0 0 0 1
decreased by decreased d de dec decr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 (/) 3 8 0 0 0 0 1
tested. We tested. t te tes test BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 . 1 8 0 0 0 0 1
and found and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 (). 3 9 0 0 0 0 1
This causes this T Th Thi This BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 2 -- 2 9 0 0 0 0 1
stitution in stitution s st sti stit BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 2 , 1 9 0 0 0 0 1
conserved region conserved c co con cons BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 (). 3 8 0 0 0 0 1
DNA is dna D DN DNA DNA BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 5 2 no 0 9 0 0 0 0 1
change is change c ch cha chan BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 2 ( 1 9 0 0 0 0 1
polymorphism) in polymorphism) p po pol poly BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 2 )(). 4 8 0 0 0 0 1
The breast the T Th The The BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 5 4 no 0 9 0 0 0 0 1
five separate five f fi fiv five BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 (), 3 10 0 0 0 0 1
least three least l le lea leas BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 - 1 9 0 0 0 0 1
pressor genes: pressor p pr pre pres BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 5 4 : 1 9 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 ( 1 8 0 0 0 0 1
3) (15.6 3) 3 3) 3) 3) BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 5 4 )(.), 5 8 0 0 0 0 1
between 21.9 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 ..,- 4 9 0 0 0 0 1
date cancer date d da dat date BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 (.)( 4 8 0 0 0 0 1
receptor 5) receptor r re rec rece BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 )(.)[], 7 10 0 0 0 0 1
and a and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 ., 2 8 0 0 0 0 1
region of region r re reg regi BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 5 4 . 1 5 0 0 0 0 1
Discussion Discussion discussion D Di Dis Disc BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 5 no 0 10 0 0 0 0 1
This high-resolution this T Th Thi This BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 5 - 1 9 0 0 0 0 1
has allowed has h ha has has BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 5 no 0 10 0 0 0 0 1
on 8p on o on on on BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 5 . 1 9 0 0 0 0 1
CGH studies cgh C CG CGH CGH BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 5 -- 2 9 0 0 0 0 1
rent translocation rent r re ren rent BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 5 [,,,,]. 7 9 0 0 0 0 1
We now we W We We We BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 5 - 1 9 0 0 0 0 1
8p with 8p 8 8p 8p 8p BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 6 - 1 10 0 0 0 0 1
on distal on o on on on BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 6 –. 2 9 0 0 0 0 1
We identified we W We We We BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 6 : 1 10 0 0 0 0 1
8p21.3, which 8p21.3, 8 8p 8p2 8p21 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 6 ., 2 8 0 0 0 0 1
21.8 Mb; 21.8 2 21 21. 21.8 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 6 .;, 3 8 0 0 0 0 1
between 12.9 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 6 ..; 3 9 0 0 0 0 1
loss centred loss l lo los loss BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 6 ... 3 9 0 0 0 0 1
high-resolution BAC high-resolution h hi hig high BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 6 - 1 8 0 0 0 0 1
characterising genomic characterising c ch cha char BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 6 no 0 9 0 0 0 0 1
that provides that t th tha that BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 6 no 0 8 0 0 0 0 1
for further for f fo for for BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 6 -. 2 7 0 0 0 0 1
Amplification around amplification A Am Amp Ampl BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 7 .. 2 6 0 0 0 0 1
A novel a A A A A BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 6 7 . 1 9 0 0 0 0 1
and primary and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 7 . 1 9 0 0 0 0 1
event, seen event, e ev eve even BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 7 ,(/)/ 5 9 0 0 0 0 1
tumours, perhaps tumours, t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 7 ,- 2 9 0 0 0 0 1
of tumours of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 7 []. 3 10 0 0 0 0 1
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tumour material tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 7 no 0 9 0 0 0 0 1
cancer. Furthermore, cancer. c ca can canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 7 .,- 3 8 0 0 0 0 1
tion contains tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 7 no 0 8 0 0 0 0 1
play a play p pl pla play BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 7 . 1 5 0 0 0 0 1
FGF17 (fibroblast fgf17 F FG FGF FGF1 BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 () 2 9 0 0 0 0 1
fibroblast growth fibroblast f fi fib fibr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 8 ,- 2 9 0 0 0 0 1
cated in cated c ca cat cate BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 8 ., 2 9 0 0 0 0 1
FGF3, FGF4 fgf3, F FG FGF FGF3 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 ,,- 3 9 0 0 0 0 1
gration [42,43] gration g gr gra grat BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 8 [,] 3 9 0 0 0 0 1
in 41% in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 6 8 []. 3 9 0 0 0 0 1
some prostate some s so som some BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 no 0 9 0 0 0 0 1
risk of risk r ri ris risk BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 [].(- 5 9 0 0 0 0 1
ophosmin/nucleoplasmin member ophosmin/nucleoplasmin o op oph opho BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 8 /) 2 8 0 0 0 0 1
assembly of assembly a as ass asse BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 no 0 9 0 0 0 0 1
involved in involved i in inv invo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 no 0 9 0 0 0 0 1
chromatin immediately chromatin c ch chr chro BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 8 . 1 9 0 0 0 0 1
family, NPM1 family, f fa fam fami BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 , 1 10 0 0 0 0 1
the tumour the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 [], 3 9 0 0 0 0 1
in several in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 6 8 no 0 9 0 0 0 0 1
acute myeloid acute a ac acu acut BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 [,]. 4 9 0 0 0 0 1
signalling in signalling s si sig sign BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 []. 3 10 0 0 0 0 1
well-known oncogene well-known w we wel well BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 8 -- 2 9 0 0 0 0 1
ment of ment m me men ment BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 8 - 1 9 0 0 0 0 1
drome multiple drome d dr dro drom BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 8 ([]). 5 9 0 0 0 0 1
Of these of O Of Of Of BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 10 - 1 8 0 0 0 0 1
in two in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 6 10 ,(--),- 7 9 0 0 0 0 1
out (DU4475), out o ou out out BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 10 (),.,- 6 9 0 0 0 0 1
expressed in expressed e ex exp expr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 10 no 0 10 0 0 0 0 1
region (BT-20). region r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 10 (-).,, 6 9 0 0 0 0 1
highest level highest h hi hig high BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 10 - 1 9 0 0 0 0 1
region amplified region r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 10 --, 3 8 0 0 0 0 1
targets of targets t ta tar targ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 10 . 1 10 0 0 0 0 1
pattern of pattern p pa pat patt BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 10 - 1 8 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 6 0 ://../-// 9 10 0 0 1 0 1
Page 10 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 6 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 0 () 2 10 0 0 0 0 0
Analysis of analysis A An Ana Anal BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 1 . 1 2 0 0 0 0 1
Figure 4 figure F Fi Fig Figu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 1 no 0 0 0 0 0 0 1
Analysis of analysis A An Ana Anal BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 1 ..()..,;, 9 9 0 0 0 0 1
heterozygous loss; heterozygous h he het hete BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 1 ;,., 4 10 0 0 0 0 1
from MIA from f fr fro from BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 1 -..;, 5 9 0 0 0 0 1
amplify a amplify a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 1 -.() 4 8 0 0 0 0 1
ARHGEF10. The arhgef10. A AR ARH ARHG BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 1 ..().- 6 9 0 0 0 0 1
low, the low, l lo low low, BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 1 ,;,. 4 9 0 0 0 0 1
0.5 Mb 0.5 0 0. 0.5 0.5 BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 . 1 10 0 0 0 0 1
1 Mb 1 1 1 1 1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 6 7 no 0 7 0 0 0 0 1
1.5 Mb 1.5 1 1. 1.5 1.5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 . 1 10 0 0 0 0 1
2 Mb 2 2 2 2 2 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 6 7 no 0 7 0 0 0 0 1
2.5 Mb 2.5 2 2. 2.5 2.5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 . 1 10 0 0 0 0 1
3 Mb 3 3 3 3 3 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS ALLDIGIT 1 0 0 0 0 0 0 0 6 7 no 0 7 0 0 0 0 1
3.5 Mb 3.5 3 3. 3.5 3.5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 . 1 10 0 0 0 0 1
8p23.2 8p23.2 8p23.2 8 8p 8p2 8p23 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 . 1 10 0 0 0 0 1
8p23.3 8p23.3 8p23.3 8 8p 8p2 8p23 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 . 1 10 0 0 0 0 1
OR4F21 OR4F21 or4f21 O OR OR4 OR4F BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 no 0 10 0 0 0 0 1
ZNF596 ZNF596 znf596 Z ZN ZNF ZNF5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 no 0 10 0 0 0 0 1
FBXO25 FBXO25 fbxo25 F FB FBX FBXO BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 7 no 0 10 0 0 0 0 1
ERICH1 DLGAP2 erich1 E ER ERI ERIC BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 10 0 0 0 0 1
MYOM2 MYOM2 myom2 M MY MYO MYOM BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 4 0 0 0 0 1
KBTBD11 KBTBD11 kbtbd11 K KB KBT KBTB BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 10 0 0 0 0 1
CSMD1 CSMD1 csmd1 C CS CSM CSMD BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 10 0 0 0 0 1
C8orf42 C8orf42 c8orf42 C C8 C8o C8or BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 10 0 0 0 0 1
CLN8 CLN8 cln8 C CL CLN CLN8 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 10 0 0 0 0 1
ARHGEF10 ARHGEF10 arhgef10 A AR ARH ARHG BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 10 0 0 0 0 1
C8orf61 C8orf61 c8orf61 C C8 C8o C8or BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 no 0 6 0 0 0 0 1
hsa-mir-596 hsa-mir-596 hsa-mir-596 h hs hsa hsa- BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 8 -- 2 10 0 0 0 0 1
PMC42 PMC42 pmc42 P PM PMC PMC4 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 9 no 0 10 0 0 0 0 1
HCC38 HCC38 hcc38 H HC HCC HCC3 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 9 no 0 10 0 0 0 0 1
HCC1569 HCC1569 hcc1569 H HC HCC HCC1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 6 9 no 0 10 0 0 0 0 1
HCC1500 HCC1500 hcc1500 H HC HCC HCC1 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 6 9 no 0 10 0 0 0 0 1
MIA PaCa-2 mia M MI MIA MIA BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 1 0 0 0 0 0 0 6 9 - 1 10 0 0 0 0 1
DU4475 DU4475 du4475 D DU DU4 DU44 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 9 no 0 10 0 0 0 0 1
ARHGEF10 ARHGEF10 arhgef10 A AR ARH ARHG BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 9 no 0 10 0 0 0 0 1
C8orf61 C8orf61 c8orf61 C C8 C8o C8or BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 9 no 0 8 0 0 0 0 1
CLN8 CLN8 cln8 C CL CLN CLN8 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 9 no 0 5 0 0 0 0 1
hsa-mir-596 hsa-mir-596 hsa-mir-596 h hs hsa hsa- BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 9 -- 2 10 0 0 0 0 1
a a a a a a a BLOCKSTART PAGEIN SAMEFONT HIGHERFONT 0 0 NOCAPS NODIGIT 1 0 1 0 0 0 0 0 6 10 no 0 10 0 0 0 0 1
b b b b b b b BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 6 10 no 0 10 0 0 0 0 1
Homo sapiens homo H Ho Hom Homo BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 2 0 0 0 0 1
GQLYQDLQNLL HDLNVIGQITQL gqlyqdlqnll G GQ GQL GQLY BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 5 0 0 0 0 1
Pan troglodytes pan P Pa Pan Pan BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 10 no 0 3 0 0 0 0 1
GQLYQDLQNLL DLNVIGQITQL gqlyqdlqnll G GQ GQL GQLY BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 5 0 0 0 0 1
Bos taurus bos B Bo Bos Bos BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 2 0 0 0 0 1
GQLYQDLQNLL HDLSVIGHITQL gqlyqdlqnll G GQ GQL GQLY BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 5 0 0 0 0 1
Mus musculus mus M Mu Mus Mus BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 2 0 0 0 0 1
GQLYQDLQNLL HDLNVVGQISQL gqlyqdlqnll G GQ GQL GQLY BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 5 0 0 0 0 1
Rattus norvegicus rattus R Ra Rat Ratt BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 4 0 0 0 0 1
GQLYQDLQNLL HDLNVVGQISQL gqlyqdlqnll G GQ GQL GQLY BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 5 0 0 0 0 1
Canis familiaris canis C Ca Can Cani BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 3 0 0 0 0 1
GQLYQDLQNLL HDLNVVGQISQL gqlyqdlqnll G GQ GQL GQLY BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 5 0 0 0 0 1
Xenopus tropicalis xenopus X Xe Xen Xeno BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 10 0 0 0 0 1
Gallus gallus gallus G Ga Gal Gall BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 3 0 0 0 0 1
GQLYHDLQNLLHDLNVVGQISQL GQLYHDLQNLLHDLNVVGQISQL gqlyhdlqnllhdlnvvgqisql G GQ GQL GQLY BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 10 no 0 5 0 0 0 0 1
c c c c c c c BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS NODIGIT 1 0 0 0 0 0 0 0 6 11 no 0 10 0 0 0 0 1
H H h H H H H BLOCKSTART PAGEEND NEWFONT LOWERFONT 0 0 ALLCAP NODIGIT 1 0 0 0 0 0 0 0 6 11 no 0 10 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT LOWERFONT 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 6 0 ://../-// 9 10 0 0 1 0 1
Page 11 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 6 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 0 () 2 10 0 0 0 0 0
8p12 and 8p12 8 8p 8p1 8p12 BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 0 ,- 2 9 0 0 0 0 1
gestion that gestion g ge ges gest BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 6 0 [,]. 4 10 0 0 0 0 1
Rearrangements between rearrangements R Re Rea Rear BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 6 0 .. 2 8 0 0 0 0 1
SGCZ (14.6 sgcz S SG SGC SGCZ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 6 0 (.), 4 8 0 0 0 0 1
changes and changes c ch cha chan BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 6 0 , 1 8 0 0 0 0 1
unlikely to unlikely u un unl unli BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 .- 2 9 0 0 0 0 1
can complex can c ca can can BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 no 0 9 0 0 0 0 1
the extracellular the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 [], 3 9 0 0 0 0 1
show that show s sh sho show BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 , 1 10 0 0 0 0 1
a consequence a a a a a BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 1 0 1 0 0 0 0 0 6 0 .(. 3 8 0 0 0 0 1
Mb) has mb) M Mb Mb) Mb) BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 6 0 ) 1 9 0 0 0 0 1
types, including types, t ty typ type BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 ,(..[]), 8 9 0 0 0 0 1
likely target likely l li lik like BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 no 0 9 0 0 0 0 1
outside the outside o ou out outs BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 . 1 9 0 0 0 0 1
consistent with consistent c co con cons BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 no 0 9 0 0 0 0 1
is not is i is is is BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 []. 3 9 0 0 0 0 1
suppressor gene suppressor s su sup supp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 , 1 8 0 0 0 0 1
(15.6 Mb), (15.6 ( (1 (15 (15. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 6 0 (.), 4 9 0 0 0 0 1
this region this t th thi this BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 ([,,], 6 9 0 0 0 0 1
of the of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 . 1 9 0 0 0 0 1
have deletions have h ha hav have BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 no 0 8 0 0 0 0 1
decreased expression decreased d de dec decr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 no 0 9 0 0 0 0 1
in 31% in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 6 0 ., 2 9 0 0 0 0 1
of several of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 no 0 9 0 0 0 0 1
have an have h ha hav have BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 no 0 10 0 0 0 0 1
that this that t th tha that BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 6 0 . 1 6 0 0 0 0 1
Losses between losses L Lo Los Loss BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 7 3 ... 3 7 0 0 0 0 1
Loss of loss L Lo Los Loss BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 7 3 ., 2 8 0 0 0 0 1
between 1.7 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 .., 3 9 0 0 0 0 1
pancreatic cell pancreatic p pa pan panc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 3 , 1 9 0 0 0 0 1
studies of studies s st stu stud BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 .. 2 9 0 0 0 0 1
Mb. 1 mb. M Mb Mb. Mb. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 7 3 .[] 3 8 0 0 0 0 1
tumours suggests tumours t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 .- 2 9 0 0 0 0 1
mary tumours. mary m ma mar mary BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 7 3 .(/) 4 8 0 0 0 0 1
loss distal loss l lo los loss BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 ., 2 9 0 0 0 0 1
difficult due difficult d di dif diff BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 - 1 9 0 0 0 0 1
taminating normal taminating t ta tam tami BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 3 no 0 9 0 0 0 0 1
material. In material. m ma mat mate BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 ., 2 9 0 0 0 0 1
between 1.0 between b be bet betw BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 .. 2 9 0 0 0 0 1
suppressor gene. suppressor s su sup supp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 . 1 8 0 0 0 0 1
common region common c co com comm BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 ,, 2 9 0 0 0 0 1
CLN8, C8orf61, cln8, C CL CLN CLN8 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 7 3 ,,--. 5 8 0 0 0 0 1
has emerged has h ha has has BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 no 0 9 0 0 0 0 1
sequencing screen sequencing s se seq sequ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 3 .[],, 5 9 0 0 0 0 1
conjunction with conjunction c co con conj BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 no 0 9 0 0 0 0 1
of ARHGEF10 of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 no 0 8 0 0 0 0 1
copy, this copy, c co cop copy BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 ,. 2 9 0 0 0 0 1
tumour suppressor. tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 . 1 8 0 0 0 0 1
supports a supports s su sup supp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 . 1 10 0 0 0 0 1
[57], which [57], [ [5 [57 [57] BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 7 3 [],- 4 9 0 0 0 0 1
[58,59] and [58,59] [ [5 [58 [58, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 7 3 [,] 3 9 0 0 0 0 1
damage in damage d da dam dama BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 3 []. 3 5 0 0 0 0 1
A parsimonious a A A A A BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 7 6 no 0 8 0 0 0 0 1
A large a A A A A BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 7 6 ,, 2 9 0 0 0 0 1
potentially suggesting potentially p po pot pote BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 6 no 0 9 0 0 0 0 1
loci, while loci, l lo loc loci BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 6 , 1 9 0 0 0 0 1
distal 8p distal d di dis dist BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 6 no 0 10 0 0 0 0 1
genes located genes g ge gen gene BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 6 . 1 7 0 0 0 0 1
number studies, number n nu num numb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 6 ,,- 3 9 0 0 0 0 1
city of city c ci cit city BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 6 , 1 8 0 0 0 0 1
regions of regions r re reg regi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 6 ; 1 9 0 0 0 0 1
ARHGEF10 as arhgef10 A AR ARH ARHG BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 7 6 . 1 9 0 0 0 0 1
There may there T Th The Ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 7 6 , 1 9 0 0 0 0 1
DLC1, located dlc1, D DL DLC DLC1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 7 6 , 1 9 0 0 0 0 1
alternative mechanisms, alternative a al alt alte BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 6 ,. 2 8 0 0 0 0 1
results lead results r re res resu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 7 6 no 0 9 0 0 0 0 1
the varied the t th the the BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 6 () 2 9 0 0 0 0 1
The most the T Th The The BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 7 7 , 1 8 0 0 0 0 1
from 8p12 from f fr fro from BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 , 1 8 0 0 0 0 1
amplification of amplification a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 -.,- 4 9 0 0 0 0 1
anced translocations anced a an anc ance BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 7 - 1 8 0 0 0 0 1
by the by b by by by BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 9 0 0 0 0 1
most distal most m mo mos most BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 ,[]., 5 9 0 0 0 0 1
we argue we w we we we BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 9 0 0 0 0 1
on 8p, on o on on on BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 ,- 2 8 0 0 0 0 1
breaks distal breaks b br bre brea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 8 0 0 0 0 1
being retained, being b be bei bein BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 , 1 9 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 . 1 8 0 0 0 0 1
whole of whole w wh who whol BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 10 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 , 1 9 0 0 0 0 1
telomere (Figure telomere t te tel telo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 7 ().- 4 9 0 0 0 0 1
gesting a gesting g ge ges gest BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 7 .. 2 8 0 0 0 0 1
There can there T Th The Ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 8 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 8 0 0 0 0 1
would give would w wo wou woul BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 , 1 8 0 0 0 0 1
data suggests data d da dat data BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 - 1 9 0 0 0 0 1
date gene date d da dat date BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 . 1 9 0 0 0 0 1
Occam's razor occam's O Oc Occ Occa BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 7 7 '/ 2 9 0 0 0 0 1
genes is genes g ge gen gene BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 7 , 1 9 0 0 0 0 1
but can but b bu but but BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 , 1 9 0 0 0 0 1
therefore explaining therefore t th the ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 9 0 0 0 0 1
of changes of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 ()– 3 8 0 0 0 0 1
deletions of deletions d de del dele BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 8 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 no 0 9 0 0 0 0 1
of the of o of of of BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 7 . 1 7 0 0 0 0 1
Cell lines cell C Ce Cel Cell BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 7 10 no 0 9 0 0 0 0 1
allowing us allowing a al all allo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 no 0 8 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 . 1 8 0 0 0 0 1
deletions in deletions d de del dele BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 , 1 8 0 0 0 0 1
tumour suppressor tumour t tu tum tumo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 no 0 9 0 0 0 0 1
frequently deleted, frequently f fr fre freq BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 ,., 3 8 0 0 0 0 1
candidate regions. candidate c ca can cand BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 .. 2 8 0 0 0 0 1
have been have h ha hav have BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 , 1 8 0 0 0 0 1
affected by affected a af aff affe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 10 ,- 2 10 0 0 0 0 1
tion of tion t ti tio tion BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 10 , 1 8 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT SAMEFONTSIZE 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 7 0 ,: 2 10 0 0 1 0 1
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Page 12 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 7 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 0 () 2 10 0 0 0 0 0
on the on o on on on BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 0 [], 3 10 0 0 0 0 1
TRAIL receptors trail T TR TRA TRAI BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 1 0 0 0 0 0 7 0 , 1 9 0 0 0 0 1
as candidate as a as as as BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 0 - 1 9 0 0 0 0 1
function [61]. function f fu fun func BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 0 [].-, 5 10 0 0 0 0 1
supporting the supporting s su sup supp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 0 no 0 9 0 0 0 0 1
8p22 and 8p22 8 8p 8p2 8p22 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 7 0 .. 2 3 0 0 0 0 1
Although the although A Al Alt Alth BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 7 1 no 0 9 0 0 0 0 1
force behind force f fo for forc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 1 - 1 9 0 0 0 0 1
tion of tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 1 , 1 9 0 0 0 0 1
might be might m mi mig migh BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 1 no 0 9 0 0 0 0 1
of breakage of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 1 .. 2 9 0 0 0 0 1
example, the example, e ex exa exam BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 1 , 1 9 0 0 0 0 1
could be could c co cou coul BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 1 no 0 10 0 0 0 0 1
breakage-fusion-bridge cycles breakage-fusion-bridge b br bre brea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 1 --[] 4 9 0 0 0 0 1
has been has h ha has has BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 7 1 []- 3 8 0 0 0 0 1
quently occur quently q qu que quen BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 7 1 . 1 8 0 0 0 0 1
Conclusion Conclusion conclusion C Co Con Conc BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 3 no 0 10 0 0 0 0 1
While early while W Wh Whi Whil BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 4 ,[,] 4 8 0 0 0 0 1
focused on focused f fo foc focu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 4 ,- 2 9 0 0 0 0 1
trated on trated t tr tra trat BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 4 -[,] 4 9 0 0 0 0 1
role of role r ro rol role BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 4 . 1 9 0 0 0 0 1
suggests that, suggests s su sug sugg BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 4 , 1 9 0 0 0 0 1
from 8p12 from f fr fro from BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 4 , 1 9 0 0 0 0 1
there are there t th the ther BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 4 . 1 9 0 0 0 0 1
While loss while W Wh Whi Whil BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 4 no 0 9 0 0 0 0 1
cases, loss cases, c ca cas case BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 4 ,- 2 10 0 0 0 0 1
tion for tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 4 no 0 8 0 0 0 0 1
observed breakage observed o ob obs obse BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 4 . 1 7 0 0 0 0 1
Competing interests competing C Co Com Comp BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 6 no 0 10 0 0 0 0 1
The authors the T Th The The BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 6 . 1 10 0 0 0 0 1
A parsimonious a A A A A BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 8 6 no 0 3 0 0 0 0 1
Figure 5 figure F Fi Fig Figu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 6 no 0 0 0 0 0 0 1
A parsimonious a A A A A BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 1 0 1 0 0 0 0 0 8 6 . 1 8 0 0 0 0 1
sample of sample s sa sam samp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 8 6 ().- 4 9 0 0 0 0 1
rangements expected rangements r ra ran rang BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 6 .- 2 9 0 0 0 0 1
dicted if dicted d di dic dict BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 6 , 1 9 0 0 0 0 1
8p23.3. This 8p23.3. 8 8p 8p2 8p23 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 6 ... 3 10 0 0 0 0 1
atypical 8p atypical a at aty atyp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 6 ,. 2 9 0 0 0 0 1
presence of presence p pr pre pres BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 6 .;,. 4 9 0 0 0 0 1
Since each since S Si Sin Sinc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 6 - 1 9 0 0 0 0 1
passing some passing p pa pas pass BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 6 . 1 9 0 0 0 0 1
removes all removes r re rem remo BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 6 . 1 5 0 0 0 0 1
TSG TSG tsg T TS TSG TSG BLOCKSTART PAGEIN NEWFONT HIGHERFONT 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
TSG TSG tsg T TS TSG TSG BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
TSG TSG tsg T TS TSG TSG BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
TSG TSG tsg T TS TSG TSG BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 11 no 0 8 0 0 0 0 1
TSG? TSG? tsg? T TS TSG TSG? BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 11 ? 1 10 0 0 0 0 1
TSG? TSG? tsg? T TS TSG TSG? BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 11 ? 1 10 0 0 0 0 1
TSG TSG tsg T TS TSG TSG BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 11 no 0 8 0 0 0 0 1
8p telomere 8p 8 8p 8p 8p BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
centromere centromere centromere c ce cen cent BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 11 no 0 9 0 0 0 0 1
8p12 8p12 8p12 8 8p 8p1 8p12 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 11 no 0 4 0 0 0 0 1
8p23 8p23 8p23 8 8p 8p2 8p23 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
8p23 8p23 8p23 8 8p 8p2 8p23 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
8p12 8p12 8p12 8 8p 8p1 8p12 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
8p12 8p12 8p12 8 8p 8p1 8p12 BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
8p22 8p22 8p22 8 8p 8p2 8p22 BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 11 no 0 10 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT LOWERFONT 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 8 0 ://../-// 9 10 0 0 1 0 1
Page 13 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 8 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 0 () 2 10 0 0 0 0 0
Authors' contributions authors' A Au Aut Auth BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 0 ' 1 10 0 0 0 0 1
SLC wrote slc S SL SLC SLC BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 0 no 0 9 0 0 0 0 1
experimental work. experimental e ex exp expe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 0 .. 2 10 0 0 0 0 1
SFC performed sfc S SF SFC SFC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 0 no 0 9 0 0 0 0 1
supervision of supervision s su sup supe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 0 .. 2 10 0 0 0 0 1
PAWE is pawe P PA PAW PAWE BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 0 - 1 9 0 0 0 0 1
script writing. script s sc scr scri BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 0 . 1 2 0 0 0 0 1
Additional material additional A Ad Add Addi BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 0 no 0 10 0 0 0 0 1
Acknowledgements Acknowledgements acknowledgements A Ac Ack Ackn BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 0 no 0 10 0 0 0 0 1
We thank we W We We We BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 0 - 1 9 0 0 0 0 1
tion, Dr tion, t ti tio tion BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 0 ,'- 3 10 0 0 0 0 1
somes, Professor somes, s so som some BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 ,', 3 9 0 0 0 0 1
assistance with assistance a as ass assi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 8 1 , 1 10 0 0 0 0 1
for tumour for f fo for for BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 . 1 9 0 0 0 0 1
printed by printed p pr pri prin BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 , 1 9 0 0 0 0 1
of Pathology, of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 ,. 2 9 0 0 0 0 1
CRUK, Breast cruk, C CR CRU CRUK BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,(). 5 9 0 0 0 0 1
References References references R Re Ref Refe BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 1 no 0 10 0 0 0 0 1
1. 1. 1. 1 1. 1. 1. BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Tirkkonen M, tirkkonen T Ti Tir Tirk BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,, 5 9 0 0 0 0 1
OP: Molecular op: O OP OP: OP: BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 : 1 7 0 0 0 0 1
CGH. Genes cgh. C CG CGH CGH. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 6 0 0 0 0 1
2. 2. 2. 2 2. 2. 2. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Loo LW, loo L Lo Loo Loo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 8 1 ,,,,,, 6 8 0 0 0 0 1
Holcomb IN, holcomb H Ho Hol Holc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,,,- 7 9 0 0 0 0 1
row JJ, row r ro row row BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 8 1 ,,,: 4 8 0 0 0 0 1
hybridization analysis hybridization h hy hyb hybr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 - 1 8 0 0 0 0 1
cer subtypes. cer c ce cer cer BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 6 0 0 0 0 1
3. 3. 3. 3 3. 3. 3. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Davidson JM, davidson D Da Dav Davi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,,- 6 8 0 0 0 0 1
Cahen C, cahen C Ca Cah Cahe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,: 5 8 0 0 0 0 1
cytogenetic analysis cytogenetic c cy cyt cyto BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 . 1 8 0 0 0 0 1
2000, 83:1309-1317. 2000, 2 20 200 2000 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 8 1 ,:-. 4 2 0 0 0 0 1
4. 4. 4. 4 4. 4. 4. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Bashyam MD, bashyam B Ba Bas Bash BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,-,- 7 8 0 0 0 0 1
kari CA, kari k ka kar kari BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,:-- 6 8 0 0 0 0 1
tive genomic tive t ti tiv tive BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 no 0 7 0 0 0 0 1
amplifications and amplifications a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 - 1 7 0 0 0 0 1
cer. Neoplasia cer. c ce cer cer. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 4 0 0 0 0 1
5. 5. 5. 5 5. 5. 5. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Emi M, emi E Em Emi Emi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,,, 6 8 0 0 0 0 1
Maeda Y, maeda M Ma Mae Maed BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,:- 5 8 0 0 0 0 1
erozygosity for erozygosity e er ero eroz BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 no 0 7 0 0 0 0 1
carcinoma, colorectal carcinoma, c ca car carc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,. 3 7 0 0 0 0 1
1992, 52:5368-5372. 1992, 1 19 199 1992 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 8 1 ,:-. 4 2 0 0 0 0 1
6. 6. 6. 6 6. 6. 6. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Wu CL, wu W Wu Wu Wu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,,,, 7 9 0 0 0 0 1
PM, Thakker pm, P PM PM, PM, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,: 2 8 0 0 0 0 1
of allelic of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 no 0 7 0 0 0 0 1
oropharyngeal squamous oropharyngeal o or oro orop BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 . 1 7 0 0 0 0 1
Cancer 1997, cancer C Ca Can Canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 1 ,:-. 4 3 0 0 0 0 1
7. 7. 7. 7 7. 7. 7. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Wright K, wright W Wr Wri Wrig BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,,,,- 8 8 0 0 0 0 1
nevix-Trench G: nevix-trench n ne nev nevi BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 -: 2 7 0 0 0 0 1
critical regions critical c cr cri crit BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 no 0 8 0 0 0 0 1
adenocarcinomas. Oncogene adenocarcinomas. a ad ade aden BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 6 0 0 0 0 1
8. 8. 8. 8 8. 8. 8. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Muscheck M, muscheck M Mu Mus Musc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,: 4 8 0 0 0 0 1
mapping of mapping m ma map mapp BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 - 1 8 0 0 0 0 1
pressor gene pressor p pr pre pres BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 - 1 7 0 0 0 0 1
some 8p23.3. some s so som some BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 ..,:-. 6 6 0 0 0 0 1
9. 9. 9. 9 9. 9. 9. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 . 1 0 0 0 0 0 1
Thompson F, thompson T Th Tho Thom BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,,, 6 8 0 0 0 0 1
Knox S, knox K Kn Kno Knox BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,.:- 7 9 0 0 0 0 1
mosome abnormalities mosome m mo mos moso BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .. 2 7 0 0 0 0 1
Twenty-eight cases twenty-eight T Tw Twe Twen BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 1 -. 2 8 0 0 0 0 1
Cancer 1993, cancer C Ca Can Canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 8 1 ,:-. 4 3 0 0 0 0 1
10. Pole 10. 1 10 10. 10. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 .,-,,,, 7 9 0 0 0 0 1
AE, Tse ae, A AE AE, AE, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,:- 5 8 0 0 0 0 1
chromosome rearrangements chromosome c ch chr chro BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 , 1 7 0 0 0 0 1
pancreatic cancer pancreatic p pa pan panc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 , 1 8 0 0 0 0 1
translocation. Oncogene translocation. t tr tra tran BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 6 0 0 0 0 1
11. Gelsi-Boyer 11. 1 11 11. 11. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 .-,,,,, 7 9 0 0 0 0 1
C, Lasorsa c, C C, C, C, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,,, 6 8 0 0 0 0 1
Adelaide J, adelaide A Ad Ade Adel BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,,, 6 9 0 0 0 0 1
Charafe-Jauffret E, charafe-jauffret C Ch Cha Char BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 -,,,,, 6 9 0 0 0 0 1
Chaffanet M: chaffanet C Ch Cha Chaf BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 :-- 3 7 0 0 0 0 1
tion in tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 7 0 0 0 0 1
12. Adelaide 12. 1 12 12. 12. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 .,,,,, 6 9 0 0 0 0 1
MJ, Popovici mj, M MJ MJ, MJ, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,,-, 7 9 0 0 0 0 1
Jacquemier J, jacquemier J Ja Jac Jacq BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,: 5 8 0 0 0 0 1
recurrent chromosome recurrent r re rec recu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 no 0 7 0 0 0 0 1
and pancreatic and a an and and BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 / 1 8 0 0 0 0 1
gene. Genes gene. g ge gen gene BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 6 0 0 0 0 1
13. Prentice 13. 1 13 13. 13. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 .,,,,, 6 9 0 0 0 0 1
N, Turbin n, N N, N, N, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,,,- 7 8 0 0 0 0 1
ley J, ley l le ley ley BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 8 1 ,,,,,: 6 8 0 0 0 0 1
gene rearrangements gene g ge gen gene BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 8 1 : 1 8 0 0 0 0 1
of an of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 8 1 - 1 7 0 0 0 0 1
sis. Oncogene sis. s si sis sis. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 8 1 .,:-. 5 4 0 0 0 0 1
14. Garcia 14. 1 14 14. 14. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 8 1 .,,,,,, 7 10 0 0 0 0 1
M, Kranjac m, M M, M, M, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,,,,,, 6 9 0 0 0 0 1
PA, Caldas pa, P PA PA, PA, BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 8 1 ,:- 3 8 0 0 0 0 1
Additional File additional A Ad Add Addi BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 9 no 0 10 0 0 0 0 1
Cancer cell cancer C Ca Can Canc BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 9 .– 2 10 0 0 0 0 1
used in used u us use used BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 9 ,. 2 6 0 0 0 0 1
Click here click C Cl Cli Clic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 9 no 0 2 0 0 0 0 1
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Additional File additional A Ad Add Addi BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 9 no 0 10 0 0 0 0 1
Validation of validation V Va Val Vali BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 9 .- 2 10 0 0 0 0 1
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FISH validation fish F FI FIS FISH BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP NODIGIT 0 1 1 0 0 0 0 0 9 9 . 1 8 0 0 0 0 1
Click here click C Cl Cli Clic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 9 no 0 2 0 0 0 0 1
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Additional File additional A Ad Add Addi BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 10 no 0 10 0 0 0 0 1
Primers. This primers. P Pr Pri Prim BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 10 .– 2 10 0 0 0 0 1
used in used u us use used BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 10 . 1 2 0 0 0 0 1
Click here click C Cl Cli Clic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 10 no 0 2 0 0 0 0 1
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2407-8-288-S3.pdf] 2407-8-288-S3.pdf] 2407-8-288-s3.pdf] 2 24 240 2407 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 0 9 10 ---.] 5 2 0 0 0 0 1
Additional File additional A Ad Add Addi BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 10 no 0 10 0 0 0 0 1
8p array 8p 8 8p 8p 8p BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 10 . 1 10 0 0 0 0 1
which array which w wh whi whic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 10 . 1 9 0 0 0 0 1
Click here click C Cl Cli Clic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 10 no 0 2 0 0 0 0 1
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2407-8-288-S4.xls] 2407-8-288-S4.xls] 2407-8-288-s4.xls] 2 24 240 2407 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 0 9 10 ---.] 5 2 0 0 0 0 1
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Copy number copy C Co Cop Copy BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 1 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 11 .– 2 9 0 0 0 0 1
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cell lines. cell c ce cel cell BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 11 . 1 1 0 0 0 0 1
Click here click C Cl Cli Clic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 11 no 0 2 0 0 0 0 1
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2407-8-288-S5.pdf] 2407-8-288-S5.pdf] 2407-8-288-s5.pdf] 2 24 240 2407 BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 0 9 11 ---.] 5 2 0 0 0 0 1
Additional File additional A Ad Add Addi BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 11 no 0 10 0 0 0 0 1
Fosmid array fosmid F Fo Fos Fosm BLOCKSTART PAGEIN NEWFONT LOWERFONT 1 1 INITCAP NODIGIT 0 0 0 0 0 0 0 0 9 11 . 1 10 0 0 0 0 1
lines with lines l li lin line BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 11 ., 2 9 0 0 0 0 1
TUSC3. TUSC3. tusc3. T TU TUS TUSC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 11 . 1 0 0 0 0 0 1
Click here click C Cl Cli Clic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 1 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 11 no 0 2 0 0 0 0 1
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2407-8-288-S6.xls] 2407-8-288-S6.xls] 2407-8-288-s6.xls] 2 24 240 2407 BLOCKEND PAGEEND SAMEFONT SAMEFONTSIZE 1 1 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 0 9 11 ---.] 5 2 0 0 0 0 1
BMC Cancer bmc B BM BMC BMC BLOCKSTART PAGESTART NEWFONT HIGHERFONT 0 1 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,: 2 10 0 0 1 0 1
http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 http://www.biomedcentral.com/1471-2407/8/288 h ht htt http BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 NOCAPS CONTAINSDIGITS 0 0 0 0 1 0 0 1 9 0 ://../-// 9 10 0 0 1 0 1
Page 14 page P Pa Pag Page BLOCKSTART PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 0 no 0 10 0 0 0 0 0
(page number (page ( (p (pa (pag BLOCKSTART PAGEIN NEWFONT LOWERFONT 0 1 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 () 2 10 0 0 0 0 0
cancer identifies cancer c ca can canc BLOCKSTART PAGEIN NEWFONT HIGHERFONT 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 ., 2 7 0 0 0 0 1
24:5235-5245. 24:5235-5245. 24:5235-5245. 2 24 24: 24:5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 :-. 3 1 0 0 0 0 1
15. Ray 15. 1 15 15. 15. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,, 6 8 0 0 0 0 1
JA, Ethier ja, J JA JA, JA, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,:- 3 8 0 0 0 0 1
amplicon in amplicon a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 ., 2 8 0 0 0 0 1
64:40-47. 64:40-47. 64:40-47. 6 64 64: 64:4 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 :-. 3 1 0 0 0 0 1
16. Adnane 16. 1 16 16. 16. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,,, 7 9 0 0 0 0 1
Jeanteur P, jeanteur J Je Jea Jean BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,:, 4 8 0 0 0 0 1
to members to t to to to BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 , 1 7 0 0 0 0 1
human breast human h hu hum huma BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 .,:-. 5 6 0 0 0 0 1
17. Paterson 17. 1 17 17. 17. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,, 6 9 0 0 0 0 1
AE, Wang ae, A AE AE, AE, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,:-- 8 8 0 0 0 0 1
cation of cation c ca cat cati BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 no 0 8 0 0 0 0 1
of a of o of of of BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 ., 2 7 0 0 0 0 1
46:427-439. 46:427-439. 46:427-439. 4 46 46: 46:4 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 :-. 3 1 0 0 0 0 1
18. Still 18. 1 18 18. 18. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,: 6 9 0 0 0 0 1
TACC1, an tacc1, T TA TAC TACC BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 ,,- 3 7 0 0 0 0 1
ing coiled ing i in ing ing BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 9 0 , 1 8 0 0 0 0 1
amplicon. Oncogene amplicon. a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 .,:-. 5 5 0 0 0 0 1
19. Neve 19. 1 19 19. 19. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,,,,- 9 10 0 0 0 0 1
ani N, ani a an ani ani BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,,, 7 9 0 0 0 0 1
Wang NJ, wang W Wa Wan Wang BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 9 0 ,,,,,, 6 8 0 0 0 0 1
McCormick F, mccormick M Mc McC McCo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 9 0 ,,,,, 5 8 0 0 0 0 1
A, Gray a, A A, A, A, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP NODIGIT 0 0 1 0 0 0 0 0 9 0 ,: 2 8 0 0 0 0 1
study of study s st stu stud BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 ., 2 8 0 0 0 0 1
10:515-527. 10:515-527. 10:515-527. 1 10 10: 10:5 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 :-. 3 1 0 0 0 0 1
20. Heidenblad 20. 2 20 20. 20. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,, 6 9 0 0 0 0 1
van Kessel van v va van van BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 9 0 ,:--- 5 7 0 0 0 0 1
ative genomic ative a at ati ativ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 no 0 7 0 0 0 0 1
targets and targets t ta tar targ BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 - 1 7 0 0 0 0 1
noma cell noma n no nom noma BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 9 0 .,:-. 5 6 0 0 0 0 1
21. Shadeo 21. 2 21 21. 21. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,: 3 8 0 0 0 0 1
breast cancer breast b br bre brea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 .,:. 4 8 0 0 0 0 1
22. Jonsson 22. 2 22 22. 22. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,-, 7 9 0 0 0 0 1
Osoegawa K, osoegawa O Os Oso Osoe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,: 6 8 0 0 0 0 1
High-resolution genomic high-resolution H Hi Hig High BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 0 - 1 8 0 0 0 0 1
assessed by assessed a as ass asse BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 - 1 7 0 0 0 0 1
zation. Genes zation. z za zat zati BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 .,:-. 5 6 0 0 0 0 1
23. Sjoblom 23. 2 23 23. 23. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,,,- 8 9 0 0 0 0 1
delker D, delker d de del delk BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,,, 7 10 0 0 0 0 1
Meeh P, meeh M Me Mee Meeh BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,, 6 8 0 0 0 0 1
Hartigan J, hartigan H Ha Har Hart BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,,- 7 8 0 0 0 0 1
dopoulos N, dopoulos d do dop dopo BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,:- 5 8 0 0 0 0 1
sus coding sus s su sus sus BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 no 0 7 0 0 0 0 1
cancers. Science cancers. c ca can canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 .,:-. 5 4 0 0 0 0 1
24. Stamps 24. 2 24 24. 24. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,': 6 9 0 0 0 0 1
integration in integration i in int inte BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 9 0 - 1 7 0 0 0 0 1
talized by talized t ta tal tali BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 - 1 8 0 0 0 0 1
SV40 T-antigen sv40 S SV SV4 SV40 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 -.,:-. 6 7 0 0 0 0 1
25. Elston 25. 2 25 25. 25. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,: 3 9 0 0 0 0 1
cancer. I. cancer. c ca can canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 ..: 3 8 0 0 0 0 1
experience from experience e ex exp expe BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 --.- 4 8 0 0 0 0 1
topathology 1991, topathology t to top topa BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 ,:-. 4 4 0 0 0 0 1
26. Parker 26. 2 26 26. 26. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,,, 7 9 0 0 0 0 1
Nicholson RI, nicholson N Ni Nic Nich BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 9 0 ,:- 3 8 0 0 0 0 1
in primary in i in in in BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 1 1 0 0 0 0 0 9 0 .,:-. 5 7 0 0 0 0 1
27. Chin 27. 2 27 27. 27. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,-, 7 9 0 0 0 0 1
Thorne NP, thorne T Th Tho Thor BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 9 0 ,,,,,, 6 9 0 0 0 0 1
Porter PL, porter P Po Por Port BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 0 ,,,,:-- 7 8 0 0 0 0 1
tion aCGH tion t ti tio tion BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 no 0 7 0 0 0 0 1
genomic subtype genomic g ge gen geno BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 9 0 . 1 7 0 0 0 0 1
2007, 8:R215. 2007, 2 20 200 2007 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 9 0 ,:. 3 1 0 0 0 0 1
28. Chin 28. 2 28 28. 28. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,,, 7 9 0 0 0 0 1
Naderi A, naderi N Na Nad Nade BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,-,,, 6 9 0 0 0 0 1
T, Robertson t, T T, T, T, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,,: 7 9 0 0 0 0 1
Using array-comparative using U Us Usi Usin BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 0 - 1 7 0 0 0 0 1
molecular portraits molecular m mo mol mole BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 ., 2 8 0 0 0 0 1
26:1959-1970. 26:1959-1970. 26:1959-1970. 2 26 26: 26:1 BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 1 0 0 0 9 0 :-. 3 1 0 0 0 0 1
29. Callagy 29. 2 29 29. 29. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,,, 7 10 0 0 0 0 1
IO, Huntsman io, I IO IO, IO, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,:- 4 7 0 0 0 0 1
breast cancer breast b br bre brea BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 9 0 no 0 7 0 0 0 0 1
Index. Clin index. I In Ind Inde BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 0 1 0 0 0 0 0 9 0 .,:-. 5 5 0 0 0 0 1
30. Krzywinski 30. 3 30 30. 30. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 9 0 .,,,,,, 7 9 0 0 0 0 1
Barber S, barber B Ba Bar Barb BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 INITCAP NODIGIT 0 1 1 0 0 0 0 0 9 0 ,-,,,,, 7 8 0 0 0 0 1
D, Masson d, D D, D, D, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,, 6 8 0 0 0 0 1
E, Tsai e, E E, E, E, BLOCKEND PAGEIN SAMEFONT SAMEFONTSIZE 1 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 9 0 ,,,,,,, 7 8 0 0 0 0 1
Jong PJ, jong J Jo Jon Jong BLOCKSTART PAGEIN NEWFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 10 6 ,,,: 4 9 0 0 0 0 1
the human the t th the the BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 10 6 .,:-. 5 7 0 0 0 0 1
31. Fiegler 31. 3 31 31. 31. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 10 6 .,,,,,,, 8 10 0 0 0 0 1
Vetrie D, vetrie V Ve Vet Vetr BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 INITCAP NODIGIT 0 1 0 0 0 0 0 0 10 6 ,,,: 4 8 0 0 0 0 1
for comparative for f fo for for BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 10 6 - 1 7 0 0 0 0 1
amplification of amplification a am amp ampl BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 10 6 .- 2 7 0 0 0 0 1
cer 2003, cer c ce cer cer BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 10 6 ,:-. 4 2 0 0 0 0 1
32. Huang 32. 3 32 32. 32. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 10 6 .,,,,,,- 8 9 0 0 0 0 1
cia MJ, cia c ci cia cia BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 10 6 ,,,,,,- 7 9 0 0 0 0 1
das C, das d da das das BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 10 6 ,,,: 4 7 0 0 0 0 1
chromosome breakpoint chromosome c ch chr chro BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 10 6 /- 2 7 0 0 0 0 1
regulin 1/heregulin regulin r re reg regu BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 10 6 /.,:-. 6 7 0 0 0 0 1
33. Howarth 33. 3 33 33. 33. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 10 6 .,,,,,, 7 9 0 0 0 0 1
S, Ichimura s, S S, S, S, BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP NODIGIT 0 0 0 0 0 0 0 0 10 6 ,,,,: 5 8 0 0 0 0 1
reveals a reveals r re rev reve BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 10 6 no 0 8 0 0 0 0 1
cancer cell cancer c ca can canc BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 10 6 -.- 3 8 0 0 0 0 1
gene 2007. gene g ge gen gene BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 1 0 0 0 0 0 0 10 6 . 1 1 0 0 0 0 1
34. Alsop 34. 3 34 34. 34. BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 ALLCAP CONTAINSDIGITS 0 0 0 0 0 0 0 0 10 6 .,,:- 5 8 0 0 0 0 1
points on points p po poi poin BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 1 0 0 0 0 0 10 6 ,,- 3 7 0 0 0 0 1
atic carcinoma atic a at ati atic BLOCKIN PAGEIN SAMEFONT SAMEFONTSIZE 0 0 NOCAPS NODIGIT 0 0 0 0 0 0 0 0 10 6 . 1 3 0 0 0 0 1
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